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影响股骨颈骨折后行髋关节半关节置换术患者手术部位感染率的因素。

Factors affecting the rate of surgical site infection in patients after hemiarthroplasty of the hip following a fracture of the neck of the femur.

作者信息

de Jong L, Klem T M A L, Kuijper T M, Roukema G R

机构信息

Maasstad Hospital, Maasstadweg 21, 3079 DZ Rotterdam, The Netherlands.

Franciscus Hospital, Kleiweg 500, 3045 PM Rotterdam, The Netherlands.

出版信息

Bone Joint J. 2017 Aug;99-B(8):1088-1094. doi: 10.1302/0301-620X.99B8.BJJ-2016-1119.R1.

Abstract

AIMS

Surgical site infection can be a devastating complication of hemiarthroplasty of the hip, when performed in elderly patients with a displaced fracture of the femoral neck. It results in a prolonged stay in hospital, a poor outcome and increased costs. Many studies have identified risk and prognostic factors for deep infection. However, most have combined the rates of infection following total hip arthroplasty and internal fixation as well as hemiarthroplasty, despite the fact that they are different entities. The aim of this study was to clarify the risk and prognostic factors causing deep infection after hemiarthroplasty alone.

PATIENTS AND METHODS

Data were extracted from a prospective hip fracture database and completed by retrospective review of the hospital records. A total of 916 patients undergoing a hemiarthroplasty in two level II trauma teaching hospitals between 01 January 2011 and 01 May 2016 were included. We analysed the potential peri-operative risk factors with univariable and multivariable logistic regression analysis.

RESULTS

A total of 92 patients (10%) had a surgical site infection, and 44 (4.9%) developed a deep infection. After univariable analyses, the multivariable model showed that the level of experience of the surgeon measured by the number of hemiarthroplasties performed per year was a significant prognostic factor (odds ratio (OR) 0.93, p = 0.042) for the development of an infection. Secondly, the development of a haematoma (OR 9.6, p < 0.001), a re-operation (OR 4.7, p = 0.004) and an operating time of < 45 mins (OR 5.1, p = 0.002) or > 90 mins (OR 2.7, p = 0.034) were also significant factors.

CONCLUSION

There was a significant association between the experience of the surgeon and the rate of deep infection. Secondly, a haematoma, a re-operation and both shorter and longer operating times were associated with an increased risk of deep infection after hemiarthroplasty. No association was found between deep infection and the anatomical approach, the time when surgery was undertaken and the use of a drain. Cite this article: 2017;99-B:1088-94.

摘要

目的

对于股骨颈移位骨折的老年患者行髋关节半关节置换术时,手术部位感染可能是一种毁灭性的并发症。它会导致住院时间延长、预后不良及费用增加。许多研究已确定深部感染的风险和预后因素。然而,尽管全髋关节置换术、内固定术及半关节置换术是不同的实体,但大多数研究将它们的感染率合并在一起。本研究的目的是明确单纯髋关节半关节置换术后导致深部感染的风险和预后因素。

患者与方法

数据从一个前瞻性髋部骨折数据库中提取,并通过回顾医院记录加以完善。纳入了2011年1月1日至2016年5月1日期间在两家二级创伤教学医院接受髋关节半关节置换术的916例患者。我们采用单变量和多变量逻辑回归分析来分析潜在的围手术期风险因素。

结果

共有92例患者(10%)发生手术部位感染,44例(4.9%)发生深部感染。单变量分析后,多变量模型显示,以每年进行的髋关节半关节置换术数量衡量的外科医生经验水平是感染发生的一个重要预后因素(比值比(OR)0.93,p = 0.042)。其次,血肿形成(OR 9.6,p < 0.001)、再次手术(OR 4.7,p = 0.004)以及手术时间< 45分钟(OR 5.1,p = 0.002)或> 90分钟(OR 2.7,p = 0.034)也是重要因素。

结论

外科医生的经验与深部感染率之间存在显著关联。其次,血肿形成、再次手术以及较短和较长的手术时间与髋关节半关节置换术后深部感染风险增加相关。未发现深部感染与解剖入路、手术时间及引流使用之间存在关联。引用本文:2017;99 - B:1088 - 94。

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