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半髋关节置换术后葡萄球菌人工关节感染的结局:单中心回顾性研究

Outcomes of Staphylococcal Prosthetic Joint Infection After Hip Hemiarthroplasty: Single Center Retrospective Study.

作者信息

Mahmoud Ahmed Nageeb, Brule Nicholas R, Suk Michael, Horwitz Daniel Scott

机构信息

Geisinger Medical Center, Danville, PA 17821, USA.

Faculty of Medicine, Ain Shams University, Cairo 11517, Egypt.

出版信息

Medicina (Kaunas). 2025 Mar 26;61(4):602. doi: 10.3390/medicina61040602.

DOI:10.3390/medicina61040602
PMID:40282893
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12028489/
Abstract

: When prosthetic joint infections, known for their high morbidity, are caused by high-virulence organisms such as , the outcomes are even worse. This study aims to examine the outcomes of staphylococcal prosthetic joint infections after hemiarthroplasty for hip trauma patients, which has not been particularly reported. : A retrospective study was performed in a level 1 trauma center to review all the cases of prosthetic joint infections in our database. Patients' demographics, clinical inpatient, surgical, and outpatient notes, laboratory results, and serial radiographs were assessed to extract all relevant data. : Out of 2477 hip hemiarthroplasty cases reviewed, a total of 36 prosthetic joint infection cases caused by species in 36 patients were included in this study. Patients were 26 females and 10 males with a mean age of 76.5 years at the time of surgery. Fifteen cases had infections with methicillin-resistant (MRSA) while twenty-one cases had infections with other species. The mean follow-up for all cases is 43.5 months. Twenty-nine cases underwent at least a single trial for surgical debridement and implant retention surgery, and only nine (31%) had successful debridement and implant retention. The 3-month, 1-year, and 3-year cumulative mortality for all cases was 22.2, 30.5, and 41.7%, respectively. : Staphylococcal hemiarthroplasty infection is a devastating complication that is associated with a low success (31%) of implant retention surgery, significantly high morbidity, and high cumulative mortality.

摘要

当由高毒力微生物(如……)引起的以高发病率著称的人工关节感染发生时,后果会更糟。本研究旨在探讨髋部创伤患者半关节置换术后葡萄球菌性人工关节感染的结局,此前尚无专门报道。:在一级创伤中心进行了一项回顾性研究,以审查我们数据库中所有人工关节感染病例。评估患者的人口统计学资料、临床住院、手术和门诊记录、实验室结果以及系列X线片,以提取所有相关数据。:在审查的2477例髋部半关节置换病例中,本研究共纳入了36例由……菌种引起的36例人工关节感染病例。患者为26名女性和10名男性,手术时平均年龄为76.5岁。15例感染耐甲氧西林……(MRSA),21例感染其他……菌种。所有病例的平均随访时间为43.5个月。29例至少接受了一次手术清创和植入物保留手术的尝试,只有9例(31%)清创和植入物保留成功。所有病例的3个月、1年和3年累积死亡率分别为22.2%、30.5%和41.7%。:葡萄球菌性半关节置换感染是一种毁灭性并发症,与植入物保留手术成功率低(31%)、发病率显著高和累积死亡率高有关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/13ac/12028489/bfcb238cc183/medicina-61-00602-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/13ac/12028489/0645ce3313b3/medicina-61-00602-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/13ac/12028489/bfcb238cc183/medicina-61-00602-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/13ac/12028489/0645ce3313b3/medicina-61-00602-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/13ac/12028489/bfcb238cc183/medicina-61-00602-g002.jpg

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J Clin Med. 2024 Nov 10;13(22):6756. doi: 10.3390/jcm13226756.
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