Cho Eun Jeong, Park Sung-Ji, Lee Ga Yeon, Kim Eun Kyoung, Chang Sung-A, Choi Jin-Oh, Lee Sang-Chol, Park Seung Woo, Park Pyo Won
Division of Cardiology, Department of Internal Medicine, Cardiovascular Imaging Center, Heart Vascular Stroke Institute, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Division of Cardiology, Department of Internal Medicine, National Cancer Center, Goyang, Korea.
J Cardiovasc Ultrasound. 2017 Jun;25(2):47-56. doi: 10.4250/jcu.2017.25.2.47. Epub 2017 Jun 29.
The extent of mitral annular (MA) remodeling and dysfunction is correlated with the severity of mitral regurgitation (MR) as well as left atrial (LA) and left ventricular (LV) dilation. MA dysfunction may be a useful prognostic factor for operative timing and MR recurrence after successful mitral valve (MV) repair. The aim of this study was to evaluate additive prognostic factors of MA non-planarity using real-time 3D transesophageal echocardiography (RT3D-TEE) analysis in patients with chronic severe MR and preserved LV systolic function.
Forty-seven patients with chronic severe MR and preserved LV systolic function scheduled for MV repair were prospectively enrolled. Echocardiographic studies were performed before surgery and postoperatively within 2 weeks and at least 6 months after surgery. RT3D-TEE was performed before the operation and immediately post-operative.
Mean age was 55.4 ± 15.1 years and 24 were male. Annulus height/body surface area (BSA) obtained via RT3D-TEE was correlated with the degree of postoperative LA remodeling. Patients were divided into two groups by average baseline annulus height/BSA. Patients with normal annular height had a smaller postoperative LV end-diastolic dimension, LV end-systolic dimension and LA volume index than patients with decreased annular height. Preoperative annulus height/BSA values strongly predicted postoperative LA remodeling.
MA height may be a useful prognostic factor for determining the timing of surgery in patients with chronic primary MR. Annulus height/BSA assessed via RT3D-TEE may provide additional information predictive of postoperative LA remodeling after successful MV repair.
二尖瓣环(MA)重塑和功能障碍的程度与二尖瓣反流(MR)的严重程度以及左心房(LA)和左心室(LV)扩张相关。MA功能障碍可能是手术时机和二尖瓣(MV)修复成功后MR复发的有用预后因素。本研究的目的是使用实时三维经食管超声心动图(RT3D-TEE)分析评估慢性重度MR且LV收缩功能保留患者MA非平面性的附加预后因素。
前瞻性纳入47例计划进行MV修复的慢性重度MR且LV收缩功能保留的患者。在手术前、术后2周内以及术后至少6个月进行超声心动图检查。术前和术后立即进行RT3D-TEE检查。
平均年龄为55.4±15.1岁,男性24例。通过RT3D-TEE获得的瓣环高度/体表面积(BSA)与术后LA重塑程度相关。根据平均基线瓣环高度/BSA将患者分为两组。瓣环高度正常的患者术后LV舒张末期内径、LV收缩末期内径和LA容积指数均小于瓣环高度降低的患者。术前瓣环高度/BSA值强烈预测术后LA重塑。
MA高度可能是确定慢性原发性MR患者手术时机的有用预后因素。通过RT3D-TEE评估的瓣环高度/BSA可能提供额外信息,预测MV修复成功后术后LA重塑情况。