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卵巢性索间质肿瘤:伊斯兰堡希法国际医院的经验

Sex cord stromal tumours of the ovary, experience at Shifa International Hospital Islamabad.

作者信息

Qureshi Asim, Hassan Masroor, Mamoon Nadira, Ali Zafar, Ahmed Imran Nazir

机构信息

Pathology Department, Shifa International Hospital, Islamabad, Pakistan.

出版信息

J Pak Med Assoc. 2017 Jul;67(7):1107-1108.

PMID:28770898
Abstract

This descriptive study was carried out at Pathology Department, Shifa International Hospital from 2007 to 2016; all sex cord stromal tumours diagnosed during this time period were included. Epithelial, germ cell and metastatic tumours were excluded from the study. A total of 1254 Ovarian tumours were brought to Shifa of which47 (4%) were labeled as sex cord stromal tumours. Of these 36( 76 %)were granulosa cell tumour (adult33, juvenile3), 7 were labeled as sertoli leydig cell tumours (15%), 3 as thecoma/ fibroma group (7%)and only one case was labeled as microcystic stromal tumour of the ovary (2%). Overall age range for sex cord stromal tumours was 42 (12-71). Immunohistochemistry was done in 41 out of 47 cases. Sex cord stromal tumours of the ovary are rare tumours comprising 4% of the total. Adult Granulosa cell tumour is the commonest tumour seen in our study.

摘要

这项描述性研究于2007年至2016年在希法国际医院病理科开展;纳入了在此期间诊断的所有性索间质肿瘤。上皮性肿瘤、生殖细胞肿瘤和转移性肿瘤被排除在本研究之外。共有1254例卵巢肿瘤被送至希法医院,其中47例(4%)被标记为性索间质肿瘤。在这些病例中,36例(76%)为颗粒细胞瘤(成人型33例,幼年型3例),7例被标记为支持-间质细胞瘤(15%),3例为卵泡膜瘤/纤维瘤组(7%),仅有1例被标记为卵巢微囊性间质肿瘤(2%)。性索间质肿瘤的总体年龄范围为42岁(12 - 71岁)。47例病例中有41例进行了免疫组化检查。卵巢性索间质肿瘤是罕见肿瘤,占总数的4%。成人颗粒细胞瘤是我们研究中最常见的肿瘤。

相似文献

1
Sex cord stromal tumours of the ovary, experience at Shifa International Hospital Islamabad.卵巢性索间质肿瘤:伊斯兰堡希法国际医院的经验
J Pak Med Assoc. 2017 Jul;67(7):1107-1108.
2
Ovarian sex cord-stromal tumours and their mimics.卵巢性索-间质肿瘤及其类似物。
Pathology. 2018 Jan;50(1):5-15. doi: 10.1016/j.pathol.2017.09.007. Epub 2017 Nov 11.
3
Ovarian sex cord stromal tumours in children and young girls - a more than two decade clinicopathological experience in a developing country, Pakistan.儿童及年轻女性的卵巢性索间质肿瘤——巴基斯坦一个发展中国家二十多年的临床病理经验
Asian Pac J Cancer Prev. 2014;15(3):1351-5. doi: 10.7314/apjcp.2014.15.3.1351.
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Use of monoclonal antibody against human inhibin as a marker for sex cord-stromal tumors of the ovary.使用抗人抑制素单克隆抗体作为卵巢性索间质肿瘤的标志物。
Am J Surg Pathol. 1997 May;21(5):583-9. doi: 10.1097/00000478-199705000-00012.
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Inhibin immunohistochemistry applied to ovarian neoplasms: a novel, effective, diagnostic tool.抑制素免疫组织化学应用于卵巢肿瘤:一种新型、有效的诊断工具。
Hum Pathol. 1997 Nov;28(11):1247-54. doi: 10.1016/s0046-8177(97)90197-0.
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[Thecoma, granulosa cell carcinoma and arrhenoblastoma of the ovaries].[卵巢纤维瘤、颗粒细胞瘤及卵巢支持间质细胞瘤]
Srp Arh Celok Lek. 1967 Dec;95(12):1153-62.
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The site of inhibin production in ovarian neoplasms.
Histopathology. 1996 Nov;29(5):465-8. doi: 10.1046/j.1365-2559.1996.d01-511.x.
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Inhibin and epithelial membrane antigen immunohistochemistry assist in the diagnosis of sex cord-stromal tumors and provide clues to the histogenesis of hypercalcemic small cell carcinomas.抑制素和上皮膜抗原免疫组织化学有助于性索间质肿瘤的诊断,并为高钙血症性小细胞癌的组织发生提供线索。
Int J Gynecol Pathol. 1998 Jan;17(1):46-53. doi: 10.1097/00004347-199801000-00009.
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Inhibin expression in ovarian tumors and tumor-like lesions: an immunohistochemical study.抑制素在卵巢肿瘤及肿瘤样病变中的表达:一项免疫组织化学研究。
Mod Pathol. 1998 Jul;11(7):656-64.
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[Ovarian tumors with endocrine function].[具有内分泌功能的卵巢肿瘤]
Zhonghua Bing Li Xue Za Zhi. 2004 Jun;33(3):217-20.

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The value of contrast-enhanced ultrasonography in differential diagnosis of benign and malignant ovarian sex cord stromal tumors.超声造影在卵巢性索间质肿瘤良恶性鉴别诊断中的价值
Gland Surg. 2022 Jun;11(6):1086-1093. doi: 10.21037/gs-22-301.
2
A 46-Year-Old Woman with Primary Infertility and a Diagnosis of Microcystic Stromal Tumor of the Ovary Confirmed by Histology and Gene Sequencing: A Case Report and Review of the Literature.一位 46 岁原发性不孕女性,经组织学和基因测序证实为卵巢小囊状间质肿瘤:病例报告及文献复习。
Am J Case Rep. 2021 Oct 20;22:e933528. doi: 10.12659/AJCR.933528.
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Ovarian microcystic stromal tumors: clinical, radiological, and pathological studies of two cases.
卵巢微囊性间质瘤:两例临床、影像学及病理学研究
Int J Clin Exp Pathol. 2019 Jun 1;12(6):2241-2248. eCollection 2019.