Ding Fangwei, Zhang Yiliang, Zhao Rong, Jiang Yanqiu, Bao Robert Li-Yuan, Lin Kaifeng, Shi Lei
MIIT Key Laboratory of Critical Materials Technology for New Energy Conversion and Storage, School of Chemistry and Chemical Engineering, Harbin Institute of Technology, Harbin 150001, China.
Chem Commun (Camb). 2017 Aug 25;53(66):9262-9264. doi: 10.1039/c7cc04709f. Epub 2017 Aug 3.
A transition-metal-free method for the B(CF)-promoted hydrogenations of N-heterocycles using ammonia borane under mild reaction conditions has been developed. The reaction affords a broad range of hydrogenated products in moderate to good yields. The enantioselective versions for the corresponding products were also investigated via our approach, showing good feasibility.
已开发出一种无过渡金属的方法，用于在温和反应条件下利用硼氨烷进行B（CF）促进的氮杂环氢化反应。该反应能以中等至良好的产率得到多种氢化产物。还通过我们的方法研究了相应产物的对映选择性版本，显示出良好的可行性。
