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在有支架和无支架区域使用聚酯和聚氨酯移植物材料的血管内支架型人工血管的顺应性研究

Compliance Study of Endovascular Stent Grafts Incorporated with Polyester and Polyurethane Graft Materials in both Stented and Unstented Zones.

作者信息

Guan Ying, Wang Lu, Lin Jing, King Martin W

机构信息

Key Laboratory of Textile Science and Technology, Ministry of Education, College of Textiles, Donghua University, 2999 North Renmin Road, Songjiang, Shanghai 201620, China.

College of Textiles, North Carolina State University, Raleigh, NC 27695-8301, USA.

出版信息

Materials (Basel). 2016 Aug 5;9(8):658. doi: 10.3390/ma9080658.

Abstract

Compliance mismatch between stent graft and host artery may induce complications and blood flow disorders. However, few studies have been reported on stent graft compliance. This study aims to explore the deformation and compliance of stent graft in stented and unstented zones under three pressure ranges. Compliance of two stent grafts incorporated with polyurethane graft (nitinol-PU) and polyester graft (nitinol-PET) materials respectively were tested; the stents used in the two stent grafts were identical. For the circumferential deformation of the stent grafts under each pressure range, the nitinol-PET stent graft was uniform in both zones. The nitinol-PU stent graft was circumferentially uniform in the stented zone, however, it was nonuniform in the unstented zone. The compliance of the PU graft material was 15 times higher than that of the PET graft. No significant difference in compliance was observed between stented and unstented zones of the nitinol-PET stent graft regardless of the applied pressure range. However, for the nitinol-PU stent graft, compliance of the unstented PU region was approximately twice that of the stented region; thus, compliance along the length of the nitinol-PU stent graft was not constant and different from that of the nitinol-PET stent graft.

摘要

支架移植物与宿主动脉之间的顺应性不匹配可能会引发并发症和血流紊乱。然而,关于支架移植物顺应性的研究报道较少。本研究旨在探讨在三种压力范围内,支架移植物在有支架区域和无支架区域的变形情况及顺应性。分别测试了两种分别采用聚氨酯移植物(镍钛诺 - 聚氨酯)和聚酯移植物(镍钛诺 - 聚酯)材料的支架移植物的顺应性;两种支架移植物中使用的支架是相同的。对于每个压力范围内支架移植物的周向变形,镍钛诺 - 聚酯支架移植物在两个区域均表现均匀。镍钛诺 - 聚氨酯支架移植物在有支架区域周向均匀,但在无支架区域不均匀。聚氨酯移植物材料的顺应性比聚酯移植物高15倍。无论施加的压力范围如何,镍钛诺 - 聚酯支架移植物的有支架区域和无支架区域在顺应性方面均未观察到显著差异。然而,对于镍钛诺 - 聚氨酯支架移植物,无支架聚氨酯区域的顺应性约为有支架区域的两倍;因此,镍钛诺 - 聚氨酯支架移植物沿长度方向的顺应性并非恒定,且与镍钛诺 - 聚酯支架移植物不同。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2cb2/5509269/cc72b021f7e9/materials-09-00658-g001.jpg

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