Greenwood Simon, Leone Antonio, Cassar-Pullicino Victor N
Department of Diagnostic Imaging, The Robert Jones and Agnes Hunt Orthopaedic Hospital NHS Foundation Trust, Twmpath Lane, Gobowen, Oswestry SY10 7AG, UK.
Emergency/Musculoskeletal Section, Institute of Radiology, Catholic University, School of Medicine, Policlinico A. Gemelli, Largo A. Gemelli, 1, Rome 00135, Italy.
Radiol Clin North Am. 2017 Sep;55(5):1035-1053. doi: 10.1016/j.rcl.2017.04.009.
SAPHO and recurrent multifocal osteomyelitis are complex inflammatory conditions that clinical radiologists play an essential part in diagnosing. They present with a wide range of musculoskeletal and skin manifestations, and exhibit several key diagnostic features that, when present, make the diagnoses unequivocal. The overall population group is young. Diagnostic delay is common with a relapsing and remitting clinical course and often subtle early radiologic findings. This article provides an up-to-date insight into both conditions, including their multifaceted pathogenesis, effective therapeutic options, and advanced imaging features, to arm radiologists with the knowledge required to make the diagnoses confidently in a timely manner.
滑膜炎、痤疮、脓疱病、骨肥厚、骨髓炎综合征（SAPHO）和复发性多灶性骨髓炎是复杂的炎症性疾病，临床放射科医生在其诊断中起着至关重要的作用。它们表现出广泛的肌肉骨骼和皮肤表现，并具有几个关键的诊断特征，一旦出现这些特征，诊断就很明确。总体人群以年轻人为主。诊断延迟很常见，临床病程呈复发缓解型，早期影像学表现往往不明显。本文对这两种疾病提供了最新的见解，包括其多方面的发病机制、有效的治疗选择和先进的影像学特征，以使放射科医生具备及时、自信地做出诊断所需的知识。
