Sharma R K
Classified Specialst (Paed) and Neonatologist, Command Hospital (Western Command), Chandimandir 134107.
Med J Armed Forces India. 1998 Jan;54(1):44-46. doi: 10.1016/S0377-1237(17)30407-0. Epub 2017 Jun 26.
Neonatal sepsis continues to be a major cause of morbidity and mortality in India. To aid the diagnosis several direct and indirect methods are available. Sepsis screen has resulted in decrease in indiscriminate use of antibiotics. C-reactive protein can be easily estimated and is a useful indicator for favourable outcome or complication. The bacterial flora causing sepsis has changed over the years. Antimicrobial chemotherapy should be based on the prevalent organisms in the neonatal ICU. Outcome can be improved by judicious use of newer antibiotics and exchange transfusion when indicated.
新生儿败血症仍是印度发病和死亡的主要原因。为辅助诊断,有多种直接和间接方法可用。败血症筛查减少了抗生素的滥用。C反应蛋白易于检测,是判断预后良好或出现并发症的有用指标。多年来,引起败血症的细菌菌群已发生变化。抗菌化疗应基于新生儿重症监护病房中的常见病原体。合理使用新型抗生素并在必要时进行换血治疗可改善预后。