Seo Jeong Eun, Lee Hong Soo, Lee Sang Wha, Shim Kyung Won, Byun A Ri, Kim Jung Hwa, An Hee Jeong, Chun Hyejin
Department of Family Medicine, Ewha Womans University School of Medicine, Seoul, Korea.
Department of Family Medicine, Bundang CHA Medical Center, CHA University, Seongnam, Korea.
Korean J Fam Med. 2017 Jul;38(4):199-205. doi: 10.4082/kjfm.2017.38.4.199. Epub 2017 Jul 20.
The sodium intake of Koreans was higher than that recommended by the World Health Organization. Urinary sodium, which is correlated with sodium intake, can be easily calculated by the Tanaka's equation. This study aimed to evaluate the association between urinary sodium and metabolic syndrome in Korean adults using the 2010-2011 Korean National Health and Nutrition Examination Survey (KNHANES).
A total of 5,870 participants from the 2010-2011 KNHANES were included in this study. Twenty-four hour urinary sodium was calculated by the Tanaka's equation using spot urine. Participants were divided into tertiles based on urinary sodium levels. The association between urinary sodium and metabolic syndrome was analyzed using multivariate logistic regression analysis.
The odds ratios (ORs) and 95% confidence intervals (CIs) of metabolic syndrome for the 2nd and 3rd tertile of urinary sodium levels was 1.51 (1.16-1.97) and 1.56 (1.23-1.97) compared to the lowest tertile of urinary sodium in men. The ORs and 95% CIs of metabolic syndrome in women were 1.20 (0.95-1.51) for the 2nd tertile and 2.16 (1.68-2.78) for the 3rd tertile. These associations remained statistically significant, even after adjusting for multiple covariates such as age, education, regular exercise, smoking, and alcohol consumption.
These findings indicate that urinary sodium is significantly associated with metabolic syndrome in Korean adults.
韩国人的钠摄入量高于世界卫生组织推荐的水平。与钠摄入量相关的尿钠可通过田中方程轻松计算得出。本研究旨在利用2010 - 2011年韩国国家健康与营养检查调查(KNHANES)评估韩国成年人尿钠与代谢综合征之间的关联。
本研究纳入了2010 - 2011年KNHANES的5870名参与者。使用随机尿样通过田中方程计算24小时尿钠。参与者根据尿钠水平分为三分位数组。使用多变量逻辑回归分析尿钠与代谢综合征之间的关联。
与男性尿钠最低三分位数组相比,尿钠水平第二和第三三分位数组代谢综合征的优势比(OR)及95%置信区间(CI)分别为1.51(1.16 - 1.97)和1.56(1.23 - 1.97)。女性中,第二三分位数组代谢综合征的OR及95%CI为1.20(0.95 - 1.51),第三三分位数组为2.16(1.68 - 2.78)。即使在调整了年龄、教育程度、规律运动、吸烟和饮酒等多个协变量后,这些关联仍具有统计学意义。
这些发现表明,韩国成年人的尿钠与代谢综合征显著相关。