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一例乙状结肠癌被诊断为面部皮肤转移,术后存活37个月。

A case of sigmoid colon adenocarcinoma diagnosed as facial cutaneous metastasis for survival after operation for 37 months.

作者信息

Ueda Junji, Yoshida Hiroshi, Makino Hiroshi, Maruyama Hiroshi, Yokoyama Tadashi, Hirakata Atsushi, Takata Hideyuki, Seki Natsuki, Kikuchi Yuta, Uchida Eiji

机构信息

Department of Surgery, Nippon Medical School Tamanagayama Hospital, 1-7-1 Nagayama, Tama-shi, Tokyo, 206-8512, Japan.

Department of Surgery, Nippon Medical School, Tokyo, Japan.

出版信息

Clin J Gastroenterol. 2017 Oct;10(5):420-425. doi: 10.1007/s12328-017-0767-7. Epub 2017 Aug 3.

Abstract

Cutaneous metastasis of an internal malignancy is uncommon and is estimated to occur in 0.7-9% of patients with internal cancer including autopsy cases. We would like to report a case of long survival of sigmoid colon adenocarcinoma diagnosed as an instance of facial cutaneous metastasis. A 68-year-old male was admitted to our hospital for a tumor mass on the left side of his cheek. In his past history, acute myocardial infarction had occurred 2 years earlier. He also had chronic renal failure and chronic obstructive pulmonary disease. Histologic findings from the biopsy sample of this facial lesion were moderately differentiated adenocarcinoma. Colonoscopy revealed a tumor 20 mm × 30 mm in diameter in the sigmoid colon. Histologic findings of the biopsy sample of this tumor also indicated moderately differentiated adenocarcinoma. The patient was diagnosed with sigmoid colon cancer with cutaneous metastasis to the face. We performed a sigmoidectomy with lymph node dissection and resection of the facial cutaneous metastasis. After being discharged, low dose chemotherapy was performed in consideration of the patient's renal function. Although long-term management of his general condition was provided, the patient died 37 months after surgery because of chronic heart failure.

摘要

内脏恶性肿瘤的皮肤转移并不常见,据估计在包括尸检病例在内的内脏癌症患者中发生率为0.7%-9%。我们想报告一例乙状结肠腺癌面部皮肤转移且存活时间较长的病例。一名68岁男性因脸颊左侧肿物入院。他既往有2年前发生急性心肌梗死病史。他还患有慢性肾衰竭和慢性阻塞性肺疾病。该面部病变活检样本的组织学检查结果为中分化腺癌。结肠镜检查发现乙状结肠有一个直径20mm×30mm的肿瘤。该肿瘤活检样本的组织学检查结果也提示为中分化腺癌。患者被诊断为乙状结肠癌伴面部皮肤转移。我们进行了乙状结肠切除术、淋巴结清扫术以及面部皮肤转移灶切除术。出院后,考虑到患者肾功能进行了低剂量化疗。尽管对其全身状况进行了长期管理,但患者术后37个月因慢性心力衰竭死亡。

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