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战斗暴露后创伤后应激障碍:临床特征与心理药物治疗

Post-traumatic stress disorder following combat exposure: clinical features and psychopharmacological treatment.

作者信息

Bleich A, Siegel B, Garb R, Lerer B

出版信息

Br J Psychiatry. 1986 Sep;149:365-9. doi: 10.1192/bjp.149.3.365.

DOI:10.1192/bjp.149.3.365
PMID:2877705
Abstract

Post-traumatic stress disorder may follow combat stress or civilian psychological traumata. In 25 retrospectively studied patients, symptoms were severe in terms of number of DSM-III items fulfilled, chronicity, and severity of psychosocial disability. Antidepressants had good or moderate results in 67% of cases treated, but major tranquilisers were much less effective; response to drug treatment was not clearly related to somatisation symptoms, significant depression, or panic attacks. Pharmacotherapy appeared to have had a positive impact on psychotherapy in 70% of cases.

摘要

创伤后应激障碍可能继发于战斗压力或平民心理创伤。在对25例患者进行的回顾性研究中,从符合《精神疾病诊断与统计手册》第三版(DSM-III)条目的数量、慢性病程以及心理社会功能障碍的严重程度来看,症状都很严重。在接受治疗的病例中,67%使用抗抑郁药取得了良好或中等效果,但使用强效镇静剂的效果要差得多;药物治疗的反应与躯体化症状、重度抑郁或惊恐发作并无明显关联。在70%的病例中,药物治疗似乎对心理治疗产生了积极影响。

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