兔子组织的醋酸代谢

Acetate metabolism by tissues of the rabbit.

作者信息

Woodnutt G, Parker D S

出版信息

Comp Biochem Physiol B. 1986;85(2):487-90. doi: 10.1016/0305-0491(86)90033-7.

Abstract

Acetyl CoA synthetase (E.C.6.2.1.1) and acetyl CoA hydrolase (E.C.3.1.2.1) activities were assayed in sub-cellular fractions of rabbit liver, heart and kidney homogenates. The intracellular location of acetyl CoA hydrolase was predominantly mitochondrial in all tissues, whereas that for acetyl CoA synthetase varied between the tissues studied. The relationship between location of enzyme activity and metabolism of acetate in different tissues is discussed.

摘要

在兔肝脏、心脏和肾脏匀浆的亚细胞组分中测定了乙酰辅酶A合成酶（E.C.6.2.1.1）和乙酰辅酶A水解酶（E.C.3.1.2.1）的活性。乙酰辅酶A水解酶在所有组织中的细胞内定位主要在线粒体中，而乙酰辅酶A合成酶在所研究的组织之间有所不同。讨论了不同组织中酶活性的定位与乙酸代谢之间的关系。