Lopez Régis, Barateau Lucie, Evangelista Elisa, Dauvilliers Yves
National Reference Center for Orphan Disease, Narcolepsy and Hypersomnia, Sleep disorder Unit, Gui de Chauliac hospital, 80 avenue Augustin Fliche, Montpellier F-34000, France; Inserm U1061, Montpellier F-34000, France; University of Montpellier, Montpellier F-34000, France.
National Reference Center for Orphan Disease, Narcolepsy and Hypersomnia, Sleep disorder Unit, Gui de Chauliac hospital, 80 avenue Augustin Fliche, Montpellier F-34000, France; Inserm U1061, Montpellier F-34000, France; University of Montpellier, Montpellier F-34000, France.
Sleep Med Clin. 2017 Sep;12(3):395-405. doi: 10.1016/j.jsmc.2017.03.016. Epub 2017 May 26.
Hypersomnolence is a clinically defined syndrome characterized by the association of prolonged nocturnal sleep, impaired arousal quality, and sleep inertia. Hypersomnolence is the major feature of central hypersomnias and is frequently reported in various mood disorders, such as major depressive disorder, bipolar disorder, or seasonal affective disorder. Assessment of hypersomnolence is challenging in depressed patients, with objective tests often in the normal range despite a high level of sleepiness complaint. On the other hand, many patients with central hypersomnias reported depressive symptoms. The self-assessment of mood symptoms in patients with central hypersomnias may overdiagnose depression with an overlap between both conditions.
嗜睡是一种临床定义的综合征，其特征为夜间睡眠延长、觉醒质量受损和睡眠惯性。嗜睡是中枢性睡眠过多的主要特征，并且在各种情绪障碍中经常有报告，如重度抑郁症、双相情感障碍或季节性情感障碍。在抑郁症患者中评估嗜睡具有挑战性，尽管患者自述有高度困倦，但客观测试结果通常在正常范围内。另一方面，许多患有中枢性睡眠过多的患者报告有抑郁症状。中枢性睡眠过多患者对情绪症状的自我评估可能会因两种情况的重叠而过度诊断为抑郁症。
