Bethesda Dermpath Laboratory, 1730 Elton Road, Suite 11, Silver Spring, MD 20903, USA; Anne Arundel Dermatology, Towson, MD 21204, USA; Pathology, Johns Hopkins University, 4940 Bayview Medical Center, Eastern Avenue, Baltimore, MD 21224, USA.
Obstet Gynecol Clin North Am. 2017 Sep;44(3):339-352. doi: 10.1016/j.ogc.2017.04.002.
Cutaneous vulvar neoplasms are commonly encountered at gynecology visits, with 2% of women having a benign vulvar melanocytic nevus and 10% to 12% of nevi being vulvar. High-grade squamous intraepithelial lesions (vulvar intraepithelial neoplasia 2 or 3) occurs in 5 per 100,000 women, with increasing incidence in the past 30 years. The recognition of these lesions and differentiation between benign, premalignant, and malignant stages are crucial for adequate diagnosis, clinical monitoring, and treatment. The presentation, diagnosis, and management of benign and malignant vulvar proliferations are discussed with focus on practical aspects of clinical care.
外阴皮肤肿瘤在妇科就诊中常见，其中 2%的女性患有良性外阴黑色素细胞痣，10%至 12%的痣位于外阴。高级别鳞状上皮内病变（外阴上皮内瘤变 2 级或 3 级）的发病率为每 10 万人中有 5 例，在过去 30 年中呈上升趋势。这些病变的识别以及良性、癌前和恶性阶段的区分对于充分的诊断、临床监测和治疗至关重要。本文讨论了良性和恶性外阴增生的表现、诊断和处理，重点是临床护理的实际方面。
