Akinbami Lara J, Rossen Lauren M, Fakhouri Tala H I, Simon Alan E, Kit Brian K
National Center for Health Statistics, Centers for Disease Control and Prevention, Hyattsville, MD; US Public Health Service, Rockville, MD.
National Center for Health Statistics, Centers for Disease Control and Prevention, Hyattsville, MD.
Ann Epidemiol. 2017 Aug;27(8):472-478.e3. doi: 10.1016/j.annepidem.2017.07.004. Epub 2017 Jul 14.
Racial disparities in childhood asthma prevalence increased after the 1990s. Obesity, which also varies by race/ethnicity, is an asthma risk factor but its contribution to asthma prevalence disparities is unknown.
We analyzed nationally representative National Health Examination and Nutrition Survey data for 2-19 year olds with logistic regression and decomposition analyses to assess the contributions of weight status to racial disparities in asthma prevalence, controlling for sex, age, and income status.
From 1988-1994 to 2011-2014, asthma prevalence increased more among non-Hispanic black (NHB) (8.4% to 18.0%) than non-Hispanic white (NHW) youth (7.2% to 10.3%). Logistic regression showed that obesity was an asthma risk factor for all groups but that a three-way "weight status-race/ethnicity-time" interaction was not significant. That is, weight status did not modify the race/ethnicity association with asthma over time. In decomposition analyses, weight status had a small contribution to NHB/NHW asthma prevalence disparities but most of the disparity remained unexplained by weight status or other asthma risk factors (sex, age and income status).
NHB youth had a greater asthma prevalence increase from 1988-1994 to 2011-2014 than NHW youth. Most of the racial disparity in asthma prevalence remained unexplained after considering weight status and other characteristics.
20世纪90年代后，儿童哮喘患病率的种族差异有所增加。肥胖也因种族/族裔而异，是哮喘的一个风险因素，但其对哮喘患病率差异的影响尚不清楚。
我们分析了具有全国代表性的国家健康检查和营养调查数据，对象为2至19岁的儿童，采用逻辑回归和分解分析来评估体重状况对哮喘患病率种族差异的影响，并对性别、年龄和收入状况进行了控制。
从1988 - 1994年到2011 - 2014年，非西班牙裔黑人（NHB）青年的哮喘患病率增长幅度（从8.4%增至18.0%）大于非西班牙裔白人（NHW）青年（从7.2%增至10.3%）。逻辑回归显示，肥胖是所有群体患哮喘的风险因素，但“体重状况 - 种族/族裔 - 时间”的三元交互作用并不显著。也就是说，随着时间推移，体重状况并未改变种族/族裔与哮喘之间的关联。在分解分析中，体重状况对NHB/NHW哮喘患病率差异的影响较小，但大部分差异仍无法通过体重状况或其他哮喘风险因素（性别、年龄和收入状况）来解释。
从1988 - 1994年到2011 - 2014年，NHB青年的哮喘患病率增长幅度大于NHW青年。在考虑体重状况和其他特征后，哮喘患病率的大部分种族差异仍无法解释。
