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对比涂层补片经腹腹膜前腹腔镜腹股沟疝修补术中缝合腹膜与不缝合腹膜的效果。

Comparison of peritoneal closure versus non-closure in laparoscopic trans-abdominal preperitoneal inguinal hernia repair with coated mesh.

机构信息

Department of Surgery, University of Massachusetts Medical School-Baystate Medical Center, 759 Chestnut Street, Springfield, MA, 01199, USA.

Academic Affairs: Office of Research, University of Massachusetts Medical School-Baystate Medical Center, Springfield, MA, USA.

出版信息

Surg Endosc. 2018 Feb;32(2):627-637. doi: 10.1007/s00464-017-5712-9. Epub 2017 Aug 4.

Abstract

BACKGROUND

Peritoneal closure during laparoscopic trans-abdominal preperitoneal (TAPP) inguinal hernia repair has been the standard of care to prevent bowel obstruction due to adhesions generated by contact with mesh. However, with newer coated meshes, leaving the peritoneal layer open may be safe. While many studies compare methods of peritoneal flap closure, there is a deficit of literature reporting the outcomes of non-closure.

METHODS

A retrospective comparison of peritoneal flap closure versus non-closure during primary laparoscopic TAPP inguinal hernia repair with coated mesh was performed for all patients at Baystate Medical Center meeting inclusion criteria between January 2005 and August 2016. Primary outcome was any procedure-related adverse outcome following repair. Secondary outcomes included operative time, resolution of pre-operative pain and/or gastrointestinal symptoms, and hernia recurrence.

RESULTS

Of 231 patients, 55 (24%) underwent peritoneal flap closure and 176 (76%) underwent non-closure. Demographic, comorbidity, and hernia characteristics were comparable between groups with the exception of obesity (p = 0.01), current smoking status (p = 0.05) and hernia side [p = 0.04 (left), 0.0003 (right)]. Mean operative time was higher in the closure group than non-closure (98.1 ± 37.1 min vs. 76.8 ± 32.9, p < 0.0001). No cases were converted to open. Average follow-up was 21.6 ± 23.8 months. Ninety-three percent of closure patients had documented resolution of pre-operative pain versus 94.0% of non-closure (p = 0.81). The closure group experienced a higher percentage of post-operative complications, though this did not reach significance (5.5 vs. 2.3%; p = 0.36). Compared to the closure group, the non-closure groups experienced similar post-operative pain (3.6 vs. 1.2%; p = 0.24) and recurrence rate (1.8 vs. 4.0%; p = 0.68). There were no bowel obstructions, surgical site infections, unplanned readmissions, or unplanned re-operations.

CONCLUSIONS

Equivalent patient outcomes were seen for both procedure types post-operatively and during follow-up. Operative times were significantly shorter for non-closure patients. Larger study population and longer follow-up is necessary to evaluate true long-term complication rates in flap non-closure.

摘要

背景

在腹腔镜经腹腹膜前(TAPP)腹股沟疝修补术中,关闭腹膜层是防止因接触网片而产生粘连导致肠梗阻的标准操作。然而,随着新型涂层网片的出现,保留腹膜层开放可能是安全的。虽然许多研究比较了腹膜瓣关闭的方法,但缺乏关于不关闭腹膜的文献报道。

方法

对 2005 年 1 月至 2016 年 8 月在贝塞斯达医疗中心接受腹腔镜 TAPP 腹股沟疝修补术(使用涂层网片)的所有符合纳入标准的患者进行了腹膜瓣关闭与不关闭的回顾性比较。主要结局是修复后任何与手术相关的不良结局。次要结局包括手术时间、术前疼痛和/或胃肠道症状的缓解情况,以及疝复发。

结果

231 例患者中,55 例(24%)行腹膜瓣关闭,176 例(76%)行不关闭。两组患者的人口统计学、合并症和疝特征相似,除肥胖(p=0.01)、当前吸烟状况(p=0.05)和疝侧(p=0.04(左侧),0.0003(右侧))外。关闭组的手术时间明显长于不关闭组(98.1±37.1min vs. 76.8±32.9,p<0.0001)。无中转开放病例。平均随访时间为 21.6±23.8 个月。93%的关闭组患者术前疼痛得到缓解,而 94.0%的不关闭组患者得到缓解(p=0.81)。虽然未达到统计学意义,但关闭组术后并发症发生率较高(5.5%比 2.3%;p=0.36)。与关闭组相比,不关闭组术后疼痛相似(3.6%比 1.2%;p=0.24),复发率相似(1.8%比 4.0%;p=0.68)。无肠梗阻、手术部位感染、计划外再入院或计划外再次手术。

结论

两种手术类型在术后和随访期间的患者结局相当。不关闭组的手术时间明显更短。需要更大的研究人群和更长的随访时间来评估不关闭腹膜瓣的真正长期并发症发生率。

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