Shapiro Melissa, Blanco David A
From the Section of Gastroenterology, Department of Pediatrics, Drexel University College of Medicine, St. Christopher's Hospital for Children, Philadelphia, PA.
From the Section of Gastroenterology, Department of Pediatrics, Drexel University College of Medicine, St. Christopher's Hospital for Children, Philadelphia, PA.
Semin Pediatr Neurol. 2017 Feb;24(1):43-53. doi: 10.1016/j.spen.2017.02.001. Epub 2017 Feb 4.
There is a growing interest in the extraintestinal manifestations of common pediatric gastrointestinal diseases, such as inflammatory bowel disease and celiac disease. This article specifically focuses on the neurological symptoms that manifest because of these disorders and their treatments. Many neurological symptoms have been reported in association with these diseases, including neuropathy, myopathy, ataxia, headache, and seizures, among others. It is currently believed that these neurological symptoms are largely overlooked by practitioners and could be a red flag for earlier diagnosis. However, additional research, especially in the pediatric population, is warranted to further elaborate on the causality and pathophysiology of these neurological symptoms.
人们对常见儿科胃肠道疾病的肠外表现，如炎症性肠病和乳糜泻，越来越感兴趣。本文特别关注由这些疾病引起的神经症状及其治疗方法。与这些疾病相关的许多神经症状已被报道，包括神经病变、肌病、共济失调、头痛和癫痫发作等。目前认为，这些神经症状在很大程度上被从业者忽视，可能是早期诊断的一个警示信号。然而，有必要进行更多的研究，特别是针对儿科人群的研究，以进一步阐明这些神经症状的因果关系和病理生理学。
