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肿瘤学中药物的重新利用:下一步举措。

Repurposing Drugs in Oncology: Next Steps.

作者信息

Verbaanderd Ciska, Meheus Lydie, Huys Isabelle, Pantziarka Pan

机构信息

Anticancer Fund, Brussels, 1853 Strombeek-Bever, Belgium; Department of Pharmaceutical and Pharmacological Sciences, University of Leuven, Leuven, Belgium.

Anticancer Fund, Brussels, 1853 Strombeek-Bever, Belgium.

出版信息

Trends Cancer. 2017 Aug;3(8):543-546. doi: 10.1016/j.trecan.2017.06.007. Epub 2017 Jul 12.

Abstract

The repurposing of existing non-cancer drugs is a potential source of new treatment options for cancer patients with high unmet medical needs. While scientific research is progressing rapidly in the field of drug repurposing, the implementation of drug repurposing still faces important financial and regulatory hurdles that should be addressed to optimise clinical adoption.

摘要

将现有非癌症药物重新用于癌症治疗,对于有大量未满足医疗需求的癌症患者而言,是潜在的新治疗选择来源。尽管药物重新利用领域的科学研究进展迅速,但药物重新利用的实施仍面临重大财务和监管障碍,要实现临床应用的优化,这些障碍必须加以解决。

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