Nguyen-Buckley Christine, Wong Melissa
Department of Anesthesiology, David Geffen School of Medicine, University of California at Los Angeles, 757 Westwood Plaza, Suite 3304, Los Angeles, CA 90095, USA.
Division of Liver and Pancreas Transplantation, Department of Surgery, David Geffen School of Medicine, University of California at Los Angeles, 757 Westwood Plaza, Los Angeles, CA 90095, USA.
Anesthesiol Clin. 2017 Sep;35(3):509-521. doi: 10.1016/j.anclin.2017.04.007. Epub 2017 Jul 5.
The diagnosis of irreversible intestinal failure confers significant morbidity, mortality, and decreased quality of life. Patients with irreversible intestinal failure may be treated with intestinal transplantation. Intestinal transplantation may include intestine only, liver-intestine, or other visceral elements. Intestinal transplantation candidates present with systemic manifestations of intestinal failure requiring multidisciplinary evaluation at an intestinal transplantation center. Central access may be difficult in intestinal transplantation candidates. Intestinal transplantation is a complex operation with potential for hemodynamic and metabolic instability. Patient and graft survival are improving, but graft failure remains the most common postoperative complication.
不可逆性肠衰竭的诊断会带来显著的发病率、死亡率，并降低生活质量。不可逆性肠衰竭患者可接受肠道移植治疗。肠道移植可能仅包括肠道、肝肠联合或其他内脏器官。肠道移植候选者会出现肠衰竭的全身表现，需要在肠道移植中心进行多学科评估。对于肠道移植候选者来说，建立中心静脉通路可能困难。肠道移植是一项复杂的手术，有导致血流动力学和代谢不稳定的风险。患者和移植物的存活率正在提高，但移植物衰竭仍然是最常见的术后并发症。
