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分层协议实施改善了神经科学重症监护病房和外科重症监护病房的低血糖治疗。

Tiered protocol implementation improves treatment of hypoglycaemia in a neurosciences critical care and surgical intensive care unit.

作者信息

Van Berkel Megan A, MacDermott Jennifer, Dungan Kathleen M, Cook Charles H, Murphy Claire V

机构信息

Department of Pharmacy, Methodist Le Bonheur Healthcare, University Hospital, United States.

Riverside Methodist Hospital, United States.

出版信息

Intensive Crit Care Nurs. 2017 Dec;43:6-11. doi: 10.1016/j.iccn.2017.06.006. Epub 2017 Aug 4.

Abstract

BACKGROUND

Although studies demonstrate techniques to limit hypoglycaemia in critically ill patients, there are limited data supporting methods to improve management of existing hypoglycaemia.

OBJECTIVE

Assess the impact and sustainability of a computerised, three tiered, nurse driven protocol for hypoglycaemia treatment.

DESIGN

Retrospective pre and post protocol study.

SETTING

Neurosciences and surgical intensive care units at a tertiary academic medical centre.

MEASUREMENTS

Patients with a hypoglycaemic episode were included during a pre-protocol or post-protocol implementation period. An additional six-month cohort was evaluated to assess sustainability.

RESULTS

Fifty-four patients were included for evaluation (35 pre- and 19 post-protocol); 122 patients were included in the sustainability cohort. Hypoglycaemia treatment significantly improved in the post-protocol cohort (20% vs. 52.6%, p=0.014); with additional improvement to 79.5% in the sustainability cohort. Time to follow-up blood glucose was decreased after treatment from 122 [Q1-Q3: 46-242] minutes pre-protocol to 25 [Q1-Q3: 9-48] minutes post protocol (p<0.0001). This reduction was maintained in the sustainability cohort [median of 29min (Q1-Q3: 20-51)].

CONCLUSION

Implementation of a nurse-driven, three-tiered protocol for treatment of hypoglyacemia significantly improved treatment rates, as well as reduced time to recheck blood glucose measurement. These benefits were sustained during a six-month period after protocol implementation.

摘要

背景

尽管有研究展示了在危重症患者中限制低血糖的技术,但支持改善现有低血糖管理方法的数据有限。

目的

评估一种由护士驱动的计算机化三层低血糖治疗方案的影响和可持续性。

设计

方案实施前后的回顾性研究。

地点

一所三级学术医疗中心的神经科学和外科重症监护病房。

测量

在方案实施前或实施后的时间段内纳入发生低血糖事件的患者。另外评估了一个为期六个月的队列以评估可持续性。

结果

纳入54例患者进行评估(方案实施前35例,方案实施后19例);122例患者纳入可持续性队列。方案实施后的队列中低血糖治疗有显著改善(20%对52.6%,p = 0.014);在可持续性队列中进一步改善至79.5%。治疗后随访血糖的时间从方案实施前的122[四分位数间距:46 - 242]分钟降至方案实施后的25[四分位数间距:9 - 48]分钟(p < 0.0001)。在可持续性队列中这一降低得以维持[中位数为29分钟(四分位数间距:20 - 51)]。

结论

实施由护士驱动的三层低血糖治疗方案显著提高了治疗率,并缩短了重新检测血糖测量的时间。这些益处在方案实施后的六个月期间得以维持。

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