Senior Resident, Department of Psychiatry, Vinayaka Mission's Kirupananda Variyar Medical College & Hospitals, Salem, India.
Senior Resident, Department of Psychiatry, Jawaharlal Institute of Postgraduate Medical Education and Research Puducherry, India.
Asian J Psychiatr. 2017 Aug;28:175-176. doi: 10.1016/j.ajp.2017.05.015. Epub 2017 May 20.
A case of an adolescent with symptoms of Mania, who developed Drug Reaction with Eosinophilia and Systemic Symptom (DRESS) syndrome on exposure to combination of oral Olanzapine and Sodium Valproate is presented. We have attempted to highlight the atypical presentation of DRESS syndrome in this patient as well as management difficulties in patient who develops DRESS syndrome with the conventional psychotropic medication. Hence, it is necessary for mental health professionals to be vigilant about this life threatening drug reaction associated with high morbidity and mortality, thus ensuring prompt diagnosis and management.
本文报告了一例青少年躁狂症状患者，在口服奥氮平和丙戊酸钠联合用药后出现药物反应伴嗜酸性粒细胞增多和全身症状（DRESS）综合征。我们试图强调该患者 DRESS 综合征的非典型表现，以及在使用常规精神药物治疗时出现 DRESS 综合征的患者的管理困难。因此，精神卫生专业人员有必要对这种与高发病率和死亡率相关的危及生命的药物反应保持警惕，从而确保及时诊断和治疗。
