Programa de Pós-Graduação em Ciências Médicas, Faculdade de Ciências Médicas, Universidade do Estado do Rio de Janeiro, Rio de Janeiro 20551-030, RJ, Brasil
Laboratório de Vibrações Mecânicas e Práticas Integrativas e Complementares, Departamento de Biofísica e Biometria, Instituto de Biologia Roberto Alcantara Gomes, Universidade do Estado do Rio de Janeiro, Rio de Janeiro 20551-030, RJ, Brasil.
Biosci Rep. 2017 Aug 21;37(4). doi: 10.1042/BSR20170846. Print 2017 Aug 31.
The consequences of treatment involving the use of a natural product and whole body vibration (WBV) exercise have been investigated. The aim of the present study was to evaluate the effects of the joint treatment with an aqueous extract of and WBV on physiological parameters in rats. Wistar rats (=20) were divided equally into four groups: control group (CG), treated with (CHE) group, exposed to 50 Hz of mechanial vibration (VBR), and treated with and exposed to 50 Hz of mechanical vibration (VBR + CHE) daily for 6 weeks. The body mass of the animals was determined weekly, the feed intake and the stool consistency were measured daily. One day after the 6 weeks of treatment, samples of blood were collected and used for biochemical analysis. Along 6 weeks, there was an increase (<0.001) in the feed intake in VBR group and a decrease in the CHE group in comparison with other groups. The levels of the enzyme aspartate aminotransferase (AST) in VBR + CHE group decreased (<0.05) in comparison with other groups. No differences were found in body mass and stool consistency. WBV altered the feed intake without directly affecting the body mass. Moreover, WBV in association with caused alteration in the enzymatic activity of AST.
本研究旨在评估联合使用天然产物水提物和全身振动（WBV）对大鼠生理参数的影响。将 20 只 Wistar 大鼠平均分为 4 组：对照组（CG）、用（CHE）处理组、暴露于 50 Hz 机械振动（VBR）组和用 处理并暴露于 50 Hz 机械振动（VBR + CHE）组，每天处理 6 周。每周测量动物体重，每天测量饲料摄入量和粪便稠度。治疗 6 周后 1 天，采集血液样本进行生化分析。在整个 6 周过程中，与其他组相比，VBR 组的饲料摄入量增加（<0.001），而 CHE 组则减少。与其他组相比，VBR + CHE 组的天冬氨酸氨基转移酶（AST）水平降低（<0.05）。体重和粪便稠度没有差异。WBV 改变了饲料摄入量，而不会直接影响体重。此外，WBV 与 联合使用会改变 AST 的酶活性。
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