de Hemptinne Quentin, de Cannière Didier, Vandenbossche Jean-Luc, Unger Philippe
Department of Cardiology, CHU Saint-Pierre, Université Libre de Bruxelles, Rue Haute, 322-1000 Brussels, Belgium.
Department of Cardiac Surgery, CHU Saint-Pierre, Université Libre de Bruxelles, Rue Haute, 322-1000 Brussels, Belgium.
Int J Cardiol Heart Vasc. 2015 Jan 29;7:1-5. doi: 10.1016/j.ijcha.2015.01.012. eCollection 2015 Jun 1.
Calcified amorphous tumor (CAT) of the heart is a rare non-neoplastic intracavitary cardiac mass. Several case reports have been published but large series are lacking.
To determine clinical features, current management and outcomes of this rare disease.
A systematic review of all articles reporting cases of CAT in order to perform a pooled analysis of its clinical features, management and outcomes.
An electronic search of all English articles using PUBMED was performed. Further studies were identified by cross-referencing from relevant papers.
We restricted inclusion to articles reporting cases of CAT in the English language literature published up to July 2014.
One author performed data extraction using predefined data fields.
A total of 27 articles, reporting 42 cases of CAT were found and included in this review.
In this review, the most frequent presenting symptoms were dyspnea and embolic events. Mitral valve and annulus were the most frequent location of CAT. Surgery was most of the time required to confirm diagnosis, and was relatively safe. Overall outcome after surgical resection was good.
心脏钙化性非晶性肿瘤（CAT）是一种罕见的非肿瘤性心腔内肿块。已有多篇病例报告发表，但缺乏大样本系列研究。
确定这种罕见疾病的临床特征、当前治疗方法及预后。
对所有报道CAT病例的文章进行系统综述，以便对其临床特征、治疗及预后进行汇总分析。
使用PUBMED对所有英文文章进行电子检索。通过对相关论文的交叉引用确定进一步的研究。
我们将纳入范围限制为截至2014年7月发表的英文文献中报道CAT病例的文章。
由一位作者使用预定义的数据字段进行数据提取。
共发现27篇报道42例CAT病例的文章并纳入本综述。
在本综述中，最常见的症状是呼吸困难和栓塞事件。二尖瓣和瓣环是CAT最常见的发病部位。大多数情况下需要手术来确诊，且手术相对安全。手术切除后的总体预后良好。
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