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不同类型导管内乳头状黏液性肿瘤患者的临床数据及生活质量、焦虑和抑郁评分比较:一项前瞻性研究

Comparison of Clinical Data and Scores of Quality of Life, Anxiety, and Depression in Patients With Different Types of Intraductal Papillary Mucinous Neoplasms: A Prospective Study.

作者信息

Pezzilli Raffaele, Cucchetti Alessandro, Calculli Lucia

机构信息

From the *Pancreas Unit, Department of Digestive System, Sant'Orsola-Malpighi Hospital; †Department of Medical and Surgical Sciences, University of Bologna; ‡Department of Diagnostic Medicine and Prevention, Sant'Orsola-Malpighi Hospital, Bologna, Italy.

出版信息

Pancreas. 2017 Sep;46(8):1029-1034. doi: 10.1097/MPA.0000000000000890.

Abstract

OBJECTIVES

This study aims to evaluate the well-being of patients with main duct intraductal papillary mucinous neoplasms (MD-IPMNs) or mixed type IPMNs (mixed-IPMNs) of the pancreas.

METHODS

Twenty-two patients with MD/mixed-IPMNs of the pancreas were studied, and an equal number of patients having branch duct IPMNs (BD-IPMNs) were used as controls. The short form (SF) -12 Health Survey, State Trait Anxiety Inventory Y-1 and Y-2, General Health Questionnaire, and Beck Depression Inventory II were used to evaluate the quality of life once a year for 2 consecutive years.

RESULTS

At basal evaluation, the SF-12 Health Survey questionnaire administered to the 44 patients showed that the values of the physical component and mental component scores were similar between the 2 groups of patients studied. The State Trait Anxiety Inventory Y-1 and Y-2, General Health Questionnaire, and Beck Depression Inventory II scores were also similar in the 2 groups at basal evaluation. No differences were found between MD/mixed-IPMNs and BD-IPMNs at the 1-year and the 2-year evaluations.

CONCLUSIONS

The well-being of patients with MD/mixed-IPMNs did not differ as compared with patients with BD-IPMNs.

摘要

目的

本研究旨在评估胰腺主胰管内乳头状黏液性肿瘤(MD-IPMNs)或混合型IPMNs(混合性IPMNs)患者的健康状况。

方法

对22例胰腺MD/混合性IPMNs患者进行研究,并将同等数量的分支胰管IPMNs(BD-IPMNs)患者作为对照。采用简短健康调查问卷(SF)-12、状态特质焦虑量表Y-1和Y-2、一般健康问卷以及贝克抑郁量表II,连续2年每年评估一次生活质量。

结果

在基础评估时,对44例患者进行的SF-12健康调查问卷显示,所研究的两组患者的身体成分和心理成分得分值相似。在基础评估时,两组患者的状态特质焦虑量表Y-1和Y-2、一般健康问卷以及贝克抑郁量表II得分也相似。在1年和2年评估时,MD/混合性IPMNs与BD-IPMNs之间未发现差异。

结论

与BD-IPMNs患者相比,MD/混合性IPMNs患者的健康状况并无差异。

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