对于胚胎来说，母亲能提供的帮助是有限的。
For Embryos, Mother Can Only Take You So Far.
机构信息
Department of Cell Biology, Duke University Medical Center, Durham NC 27710, USA.
Department of Cell Biology, Duke University Medical Center, Durham NC 27710, USA.
出版信息
Dev Cell. 2017 Aug 7;42(3):203-205. doi: 10.1016/j.devcel.2017.07.016.
PMID:28787585
Abstract
Early embryonic development is characterized by rapid cleavage divisions, which impose significant constraints on metabolic pathways. In this issue, Song et al. (2017) show that Drosophila embryos synthesize a large fraction of nucleotides on the go and that negative feedback between dATP and ribonucleotide reductase ensures tight control of dNTP concentration.
摘要
早期胚胎发育的特点是快速的卵裂分裂，这对代谢途径施加了重大限制。在本期杂志中，Song 等人（2017 年）表明，果蝇胚胎在活动中合成大量核苷酸，并且 dATP 和核糖核苷酸还原酶之间的负反馈确保了 dNTP 浓度的紧密控制。
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