Celanese Corp., Industriepark Höchst, 65926 Frankfurt am Main, Germany.
Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
J Control Release. 2017 Sep 28;262:284-295. doi: 10.1016/j.jconrel.2017.08.004. Epub 2017 Aug 5.
The potential for use of polymers in controlled drug delivery systems has been long recognized. Since their appearance in the literature, a wide range of degradable and non-degradable polymers have been demonstrated in drug delivery devices. The significance and features of ethylene-vinyl acetate (EVA) copolymers in initial research and development led to commercial drug delivery systems. This review examines the breadth of EVA use in drug delivery, and will aid the researcher in locating key references and experimental results, as well as understanding the features of EVA as a highly versatile, biocompatible polymer for drug delivery devices. Topics will include.
聚合物在控制药物释放系统中的应用潜力早已得到认可。自文献报道以来，各种可降解和不可降解的聚合物已在药物输送装置中得到了验证。乙烯-醋酸乙烯酯（EVA）共聚物在最初的研究和开发中的重要性和特点导致了商业药物输送系统的出现。本综述考察了 EVA 在药物输送中的广泛应用，并将帮助研究人员找到关键参考文献和实验结果，以及了解 EVA 作为一种多功能、生物相容的药物输送装置用聚合物的特点。主题将包括。
