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体外冲击波碎石术后15年随访中糖尿病的患病率

Prevalence of diabetes mellitus after extra corporeal shock wave lithotripsy in 15 years follow-up.

作者信息

Rashed Fahimeh Kazemi, Ahmadi Nader Rash, Zolfaghari Ali, Farshi Alireza, Amjadi Mohsen, Gholipour Mahboobeh

机构信息

Department of Urology, Imam Reza Hospital, Tabriz, Iran.

Department of Extracorporeal Shock Wave Lithotripsy, Shahid Madani Hospital, Tabriz University of Medical Sciences, Tabriz, Iran.

出版信息

Urol Ann. 2017 Jul-Sep;9(3):268-271. doi: 10.4103/0974-7796.210041.

DOI:10.4103/0974-7796.210041
PMID:28794595
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5532896/
Abstract

OBJECTIVE

To investigate the hypothesis that extracorporeal shock wave lithotripsy (ESWL) increases the risk of new onset diabetes mellitus (DM) or significant changes in fasting blood sugar (FBS).

MATERIALS AND METHODS

A total number of 307 patients enrolled in this study. All of them had undergone ESWL for kidney stone from 1991 to 1994. In 2009, after 15-19 years, we invited patients to check their blood sugar.

RESULTS

There were 307 patients, 19.8% females, and 80.1% males. The mean age of the patients was 44 for females and 42 years for males. 47.5% had kidney stone in the left side, 42.9% in the right side and 9.4% bilateral. The mean FBS increasing was 11.86 g/dl. It was 14.54 g/dl for the right side, 8.57 g/dl for left and 16.24 g/dl for bilateral ESWL.

DISCUSSIONS

The increasing of FBS is more significant in shock wave intensities higher than 15.5 KV. And there wasn't any significant relationship between age, sex, body mass index (BMI) and total number of shock waves with increasing of FBS. ESWL treatment might associate with increasing FBS without any relation to age, sex and BMI.

摘要

目的

探讨体外冲击波碎石术(ESWL)会增加新发糖尿病(DM)风险或导致空腹血糖(FBS)显著变化这一假说。

材料与方法

本研究共纳入307例患者。他们均在1991年至1994年间接受了肾结石体外冲击波碎石术。2009年,在15至19年后,我们邀请患者检查血糖。

结果

共有307例患者,女性占19.8%,男性占80.1%。女性患者的平均年龄为44岁,男性为42岁。47.5%的患者肾结石位于左侧,42.9%位于右侧,9.4%为双侧。空腹血糖平均升高11.86 g/dl。右侧体外冲击波碎石术后空腹血糖升高至14.54 g/dl,左侧为8.57 g/dl,双侧为16.24 g/dl。

讨论

冲击波强度高于15.5千伏时,空腹血糖升高更为显著。年龄、性别、体重指数(BMI)和冲击波总数与空腹血糖升高之间均无显著关系。体外冲击波碎石术治疗可能与空腹血糖升高有关,且与年龄、性别和BMI无关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31d4/5532896/788af8c43bb4/UA-9-268-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31d4/5532896/2094abdf1e32/UA-9-268-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31d4/5532896/ec472835fe7a/UA-9-268-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31d4/5532896/374cfe2f078d/UA-9-268-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31d4/5532896/788af8c43bb4/UA-9-268-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31d4/5532896/2094abdf1e32/UA-9-268-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31d4/5532896/ec472835fe7a/UA-9-268-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31d4/5532896/374cfe2f078d/UA-9-268-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31d4/5532896/788af8c43bb4/UA-9-268-g004.jpg

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Extracorporeal shock wave lithotripsy as first line treatment for urinary tract stones in children: outcome of 500 cases.体外冲击波碎石术作为儿童尿路结石的一线治疗方法:500 例病例的结果。
Int Urol Nephrol. 2012 Jun;44(3):661-6. doi: 10.1007/s11255-012-0133-0. Epub 2012 Feb 16.
2
Thoracic spinal cord epidural hematoma after extracorporeal shock wave lithotripsy.体外冲击波碎石术后胸脊髓硬膜外血肿。
J Neurosurg Spine. 2012 Feb;16(2):127-9. doi: 10.3171/2011.10.SPINE11236. Epub 2011 Nov 25.
3
Shock wave lithotripsy and diabetes mellitus: a population-based cohort study.
冲击波碎石术与糖尿病:基于人群的队列研究。
Urology. 2012 Feb;79(2):298-302. doi: 10.1016/j.urology.2011.07.1430. Epub 2011 Nov 16.
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[Renal hematomas after extracorporeal shock-wave lithotripsy (ESWL)].体外冲击波碎石术(ESWL)后肾血肿
Actas Urol Esp. 2009 Mar;33(3):296-303. doi: 10.1016/s0210-4806(09)74144-0.
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[Colonic perforation after extracorporeal shock wave lithotripsy].
Dtsch Med Wochenschr. 2009 Feb;134(9):401-3. doi: 10.1055/s-0028-1124012. Epub 2009 Feb 17.
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Shock wave lithotripsy not associated with development of diabetes mellitus at 6 years of follow-up.冲击波碎石术在6年随访期内与糖尿病的发生无关。
Urology. 2009 Jan;73(1):4-8; discussion 8. doi: 10.1016/j.urology.2008.07.066. Epub 2008 Oct 26.
7
Shock wave lithotripsy for renal stones is not associated with hypertension and diabetes mellitus.肾结石的冲击波碎石术与高血压和糖尿病无关。
Urology. 2008 Apr;71(4):586-91; discussion 591-2. doi: 10.1016/j.urology.2007.10.072.
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Prospective evaluation of acute endocrine pancreatic injury as collateral damage of shock-wave lithotripsy for upper urinary tract stones.急性内分泌胰腺损伤作为上尿路结石冲击波碎石术附带损伤的前瞻性评估。
BJU Int. 2007 Dec;100(6):1339-43. doi: 10.1111/j.1464-410X.2007.07127.x.
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ScientificWorldJournal. 2007 Sep 17;7:1563-6. doi: 10.1100/tsw.2007.236.
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