Dexmedetomidine: an attractive adjunct to anesthesia.
作者信息
Bae Hong-Beom
机构信息
Department of Anesthesiology and Pain Medicine, Chonnam National University Medical School, Gwangju, Korea.
出版信息
Korean J Anesthesiol. 2017 Aug;70(4):375-376. doi: 10.4097/kjae.2017.70.4.375. Epub 2017 Jul 13.
Abstract
摘要
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Dexmedetomidine: an attractive adjunct to anesthesia.右美托咪定：一种有吸引力的麻醉辅助药物。
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Dexmedetomidine Attenuates Neuropathic Pain by Inhibiting P2X7R Expression and ERK Phosphorylation in Rats.右美托咪定通过抑制大鼠P2X7R表达和ERK磷酸化减轻神经性疼痛。
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Additive analgesic effect of dexmedetomidine and dezocine administered intrathecally in a mouse pain model.在小鼠疼痛模型中鞘内注射右美托咪定和地佐辛的相加镇痛作用。
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本文引用的文献
1
Relationship between dexmedetomidine dose and plasma dexmedetomidine concentration in critically ill infants: a prospective observational cohort study.危重症婴儿右美托咪定剂量与血浆右美托咪定浓度的关系：一项前瞻性观察性队列研究。
Korean J Anesthesiol. 2017 Aug;70(4):426-433. doi: 10.4097/kjae.2017.70.4.426. Epub 2017 Feb 21.
2
Intraoperative dexmedetomidine sedation reduces the postoperative agitated behavior in elderly patients undergoing orthopedic surgery compared to the propofol sedation.与丙泊酚镇静相比，术中右美托咪定镇静可减少老年骨科手术患者术后激越行为。
Minerva Anestesiol. 2017 Oct;83(10):1042-1050. doi: 10.23736/S0375-9393.17.11794-3. Epub 2017 Apr 19.
3
Protection of Dexmedetomidine Against Ischemia/Reperfusion-Induced Apoptotic Insults to Neuronal Cells Occurs Via an Intrinsic Mitochondria-Dependent Pathway.右美托咪定通过内在的线粒体依赖性途径保护神经元细胞免受缺血/再灌注诱导的凋亡损伤。
J Cell Biochem. 2017 Sep;118(9):2635-2644. doi: 10.1002/jcb.25847. Epub 2017 May 16.
4
Cardiac arrest in a patient with anterior fascicular block after administration of dexmedetomidine with spinal anesthesia: A case report.右美托咪定复合脊髓麻醉后前束支阻滞患者发生心脏骤停：一例报告
Medicine (Baltimore). 2016 Oct;95(43):e5278. doi: 10.1097/MD.0000000000005278.
5
The Effect of Pre-Emptive Dexmedetomidine on the Incidence of Post-Thoracotomy Pain Syndrome in Patients Undergoing Coronary Artery Bypass Grafting.预先使用右美托咪定对接受冠状动脉旁路移植术患者开胸术后疼痛综合征发生率的影响。
Anesth Pain Med. 2016 Jun 6;6(3):e36344. doi: 10.5812/aapm.36344. eCollection 2016 Jun.
6
Dexmedetomidine vs propofol-remifentanil conscious sedation for awake craniotomy: a prospective randomized controlled trial.右美托咪定与丙泊酚-瑞芬太尼用于清醒开颅术的镇静：一项前瞻性随机对照试验。
Br J Anaesth. 2016 Jun;116(6):811-21. doi: 10.1093/bja/aew024. Epub 2016 Apr 20.
7
Effect of Dexmedetomidine Added to Standard Care on Ventilator-Free Time in Patients With Agitated Delirium: A Randomized Clinical Trial.右美托咪定联合标准治疗对躁动谵妄患者呼吸机使用时间的影响：一项随机临床试验。
JAMA. 2016 Apr 12;315(14):1460-8. doi: 10.1001/jama.2016.2707.
8
Dexmedetomidine post-treatment induces neuroprotection via activation of extracellular signal-regulated kinase in rats with subarachnoid haemorrhage.右美托咪定治疗后通过激活细胞外信号调节激酶对蛛网膜下腔出血大鼠产生神经保护作用。
Br J Anaesth. 2016 Mar;116(3):384-92. doi: 10.1093/bja/aev549.
9
Neuroprotective Effects of Dexmedetomidine Against Hypoxia-Induced Nervous System Injury are Related to Inhibition of NF-κB/COX-2 Pathways.右美托咪定对缺氧诱导的神经系统损伤的神经保护作用与抑制NF-κB/COX-2信号通路有关。
Cell Mol Neurobiol. 2016 Oct;36(7):1179-88. doi: 10.1007/s10571-015-0315-2. Epub 2015 Dec 18.
10
Perioperative dexmedetomidine reduces the incidence and severity of acute kidney injury following valvular heart surgery.围手术期使用右美托咪定可降低心脏瓣膜置换术后急性肾损伤的发生率及严重程度。
Kidney Int. 2016 Mar;89(3):693-700. doi: 10.1038/ki.2015.306.
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