Azmat Rabeea, Siddiqui Abdul Basit, Khan M Tahir Rizwan, Sunder Shiyam, Kashif Waqar
Aga Khan University Hospital, Karachi, Pakistan.
Dow University of Health Sciences, Karachi, Pakistan.
Ann Med Surg (Lond). 2017 Jul 5;21:85-88. doi: 10.1016/j.amsu.2017.06.057. eCollection 2017 Sep.
Renal biopsy is the diagnostic modality of choice for the diagnosis of renal parenchymal diseases. The advent of improved imaging techniques and biopsy needles over the years has increased the safety of the procedure and the ability to obtain adequate renal tissue for diagnosis. However, there is paucity of data in this regard from Pakistan. This study shall help in establishing the local perspective of the frequency of bleeding complications in percutaneous ultrasound guided renal biopsy.
This is a prospective case series of hospitalized patients from January till December 2015 at Nephrology Department, Aga Khan University Hospital, Karachi, Pakistan. After enrolment, each participant was followed for 24 h after renal biopsy.
A total of 220 patients were included. Mean age was 41.65 ± 8.627 years, 82 (37.2%) were male and 138 (62.8%) were female. Pre and post biopsy haemoglobin, pre and post biopsy haematocrit were 10.92 ± 1.25 and 10.60 ± 1.22, and 30.82 ± 4.73 and 30.49 ± 4.68 respectively. Out of 220 patients, 16 (7.27%) developed major complications and 26 (11.8%) developed minor complications in 24 h after renal biopsy.
Percutaneous kidney biopsy is a relatively safe procedure. Complication rates following the procedure are minimal. It is important that all nephrology programs train the trainees in performing biopsies, so that there is a wider clinical use of this important investigation even in underprivileged & developing countries.
肾活检是诊断肾实质疾病的首选诊断方法。多年来,改进的成像技术和活检针的出现提高了该操作的安全性以及获取足够肾组织用于诊断的能力。然而,巴基斯坦在这方面的数据匮乏。本研究将有助于确立经皮超声引导下肾活检出血并发症发生率的当地情况。
这是巴基斯坦卡拉奇阿迦汗大学医院肾病科2015年1月至12月住院患者的前瞻性病例系列研究。入选后,对每位参与者在肾活检后进行24小时随访。
共纳入220例患者。平均年龄为41.65±8.627岁,男性82例(37.2%),女性138例(62.8%)。活检前后的血红蛋白、血细胞比容分别为10.92±1.25和10.60±1.22,以及30.82±4.73和30.49±4.68。220例患者中,16例(7.27%)在肾活检后24小时出现严重并发症,26例(11.8%)出现轻微并发症。
经皮肾活检是一种相对安全的操作。该操作后的并发症发生率极低。所有肾病项目对学员进行活检操作培训很重要,这样即使在贫困和发展中国家,这项重要检查也能得到更广泛的临床应用。