肾移植自体肾移植及体外保留肾单位手术治疗肾移植新发肾细胞癌
Renal Autotransplantation and Extracorporeal Nephron-Sparing Surgery for De Novo Renal Cell Carcinoma in a Kidney Allograft.
作者信息
Ono Shinichiro, Kenmochi Takashi, Ito Taihei, Aida Naohiro, Otsuki Kazunori, Akutsu Naotake, Maruyama Michihiro, Kusaka Mamoru, Shiroki Ryoichi, Hoshinaga Kiyotaka
机构信息
Department of Organ Transplant Surgery, Fujita Health University, School of Medicine, Aichi, Japan.
Department of Surgery, Chiba-East National Hospital, Chiba, Japan.
出版信息
Transplant Direct. 2017 Jul 24;3(8):e122. doi: 10.1097/TXD.0000000000000714. eCollection 2017 Aug.
De novo renal cell carcinoma (RCC) rarely occurs in kidney allografts; however, the risk of RCC in these patients is 100-fold that of the general healthy population. Although total nephrectomy has been the standard treatment for kidney allograft RCC, several authors have reported that early-stage RCC in kidney allografts was successfully treated with nephron-sparing surgery. We herein describe a new procedure involving renal autotransplantation and extracorporeal nephron-sparing surgery, which was performed to treat de novo RCC near the hilum of a transplanted kidney. In the 22 months since transplantation, the patient's renal function has been favorable, and no recurrence has been observed. In conclusion, renal autotransplantation is a feasible technique for the treatment of RCC in kidney allografts, especially RCC located near the hilum.
新发肾细胞癌（RCC）很少发生于肾移植受者；然而，这些患者发生RCC的风险是一般健康人群的100倍。尽管全肾切除术一直是肾移植RCC的标准治疗方法，但有几位作者报道，肾移植受者的早期RCC通过保留肾单位手术成功得到治疗。我们在此描述一种新的手术方法，包括肾自体移植和体外保留肾单位手术，该手术用于治疗移植肾肾门附近的新发RCC。移植后的22个月里，患者肾功能良好，未观察到复发。总之，肾自体移植是治疗肾移植受者RCC的一种可行技术，尤其是位于肾门附近的RCC。
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