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肺肉瘤样癌及其他非小细胞肺癌罕见组织学亚型的治疗

Treatment of Lung Carcinosarcoma and Other Rare Histologic Subtypes of Non-small Cell Lung Cancer.

作者信息

Yang Han, Lin Yongbin, Liang Ying

机构信息

Department of Thoracic Surgery, Sun Yat-sen University Cancer Center, Guangzhou, China.

State Key Laboratory of Oncology in South China, Guangzhou, China.

出版信息

Curr Treat Options Oncol. 2017 Aug 10;18(9):54. doi: 10.1007/s11864-017-0494-9.

DOI:10.1007/s11864-017-0494-9
PMID:28795312
Abstract

Lung carcinosarcoma (PCS) and other histological subtypes of non-small cell lung cancer, such as primary pulmonary lymphoma (PPL), pulmonary carcinoid (PC), and primary pulmonary lymphoepithelioma-like carcinoma (LELC), are rare. For their low incidence, the diagnosis and treatment are still controversial. Some patients only need surgery, while others may need chemotherapy, radiotherapy, or targeted therapy. In this paper, we retrospectively reviewed the literature of some rare histological subtype of NSCLC for the recent 20 years, and try to get some conclusions.

摘要

肺肉瘤样癌(PCS)以及非小细胞肺癌的其他组织学亚型,如原发性肺淋巴瘤(PPL)、肺类癌(PC)和原发性肺淋巴上皮瘤样癌(LELC),都较为罕见。由于其发病率低,诊断和治疗仍存在争议。一些患者仅需手术治疗,而另一些患者可能需要化疗、放疗或靶向治疗。在本文中,我们回顾了近20年一些非小细胞肺癌罕见组织学亚型的文献,并试图得出一些结论。

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Treatment of Lung Carcinosarcoma and Other Rare Histologic Subtypes of Non-small Cell Lung Cancer.肺肉瘤样癌及其他非小细胞肺癌罕见组织学亚型的治疗
Curr Treat Options Oncol. 2017 Aug 10;18(9):54. doi: 10.1007/s11864-017-0494-9.
2
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J Cancer Res Clin Oncol. 2025 Apr 22;151(4):147. doi: 10.1007/s00432-025-06203-z.
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Development of a nomogram based on the clinicopathological and CT features to predict the survival of primary pulmonary lymphoepithelial carcinoma patients.基于临床病理和 CT 特征的列线图预测原发性肺淋巴上皮癌患者生存情况。
Respir Res. 2024 Mar 29;25(1):144. doi: 10.1186/s12931-024-02767-5.
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Clinical features and prognostic factors of pulmonary carcinosarcoma: A nomogram development and validation based on surveillance epidemiology and end results database.

本文引用的文献

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Pembrolizumab versus Chemotherapy for PD-L1-Positive Non-Small-Cell Lung Cancer.帕博利珠单抗对比化疗用于 PD-L1 阳性非小细胞肺癌。
N Engl J Med. 2016 Nov 10;375(19):1823-1833. doi: 10.1056/NEJMoa1606774. Epub 2016 Oct 8.
2
Primary pulmonary MALT lymphoma - case report and literature overview.原发性肺黏膜相关淋巴组织淋巴瘤——病例报告及文献综述
Eur Rev Med Pharmacol Sci. 2016 May;20(10):2065-9.
3
Deep Sequencing Analysis Reveals That KRAS Mutation Is a Marker of Poor Prognosis in Patients with Pulmonary Sarcomatoid Carcinoma.
肺肉瘤样癌的临床特征及预后因素:基于监测、流行病学和最终结果数据库的列线图构建与验证
Front Med (Lausanne). 2022 Oct 18;9:988830. doi: 10.3389/fmed.2022.988830. eCollection 2022.
4
Polymyositis as a paraneoplastic syndrome of a patient with primary pulmonary lymphoepithelioma-like carcinoma: a case report and literature review.多肌炎作为原发性肺淋巴上皮瘤样癌患者的副肿瘤综合征:一例病例报告及文献复习。
J Cardiothorac Surg. 2022 May 17;17(1):120. doi: 10.1186/s13019-022-01860-4.
5
Risk factor of brain metastases and its influence on patient prognosis after complete resection of non-small cell lung cancer.非小细胞肺癌完全切除术后脑转移的危险因素及其对患者预后的影响。
Am J Transl Res. 2022 Jan 15;14(1):406-413. eCollection 2022.
6
The clinical analysis of pulmonary lymphoepithelioma-like carcinoma with epithelioid granuloma.伴上皮样肉芽肿的肺淋巴上皮瘤样癌的临床分析
Transl Cancer Res. 2020 Feb;9(2):1023-1031. doi: 10.21037/tcr.2019.12.87.
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Stereotactic body radiation therapy for an octogenarian with pulmonary carcinosarcoma.立体定向体部放射治疗 1 例 80 岁肺多形性肉瘤患者。
Thorac Cancer. 2021 May;12(9):1445-1448. doi: 10.1111/1759-7714.13922. Epub 2021 Mar 9.
8
Use of four genes in exosomes as biomarkers for the identification of lung adenocarcinoma and lung squamous cell carcinoma.外泌体中四种基因作为鉴定肺腺癌和肺鳞癌生物标志物的应用。
Oncol Lett. 2021 Apr;21(4):249. doi: 10.3892/ol.2021.12510. Epub 2021 Feb 3.
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Oncol Lett. 2020 Jun;19(6):4031-4039. doi: 10.3892/ol.2020.11472. Epub 2020 Mar 23.
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