Russo Mark W
Division of Hepatology, Carolinas HealthCare System, Charlotte, NC.
J Clin Gastroenterol. 2017 Sep;51(8):683-692. doi: 10.1097/MCG.0000000000000886.
Since 1988 nearly 150,000 liver transplants have been performed in the United States. Over the past 3 decades the indications for liver transplant have changed from end-stage liver disease from alcohol and cholestatic liver diseases to hepatitis C and most recently nonalcoholic fatty liver disease. Liver transplant recipients are living longer with 10-year survival rates exceeding 60%. Gastroenterologists are likely to encounter or consult on postliver transplant recipients as they live longer and seek care closer to home. Complications after liver transplant are related to immunosuppression, malignancy, recurrent disease, and conditions associated with metabolic syndrome. This review will discuss postliver transplant care and complications in liver transplant recipients.
自1988年以来,美国已进行了近15万例肝脏移植手术。在过去30年里,肝脏移植的适应症已从酒精性和胆汁淤积性肝病导致的终末期肝病,转变为丙型肝炎,以及最近的非酒精性脂肪性肝病。肝脏移植受者的存活时间更长,10年生存率超过60%。随着肝脏移植受者存活时间延长且在离家更近的地方寻求治疗,胃肠病学家很可能会遇到这些患者或为他们提供会诊。肝脏移植后的并发症与免疫抑制、恶性肿瘤、疾病复发以及与代谢综合征相关的病症有关。本综述将讨论肝脏移植受者的肝移植后护理及并发症。