Kato Michitaka, Kubo Akira, Nihei Fumi, Ogano Michio, Takagi Hisato
aDepartment of Shizuoka Physical Therapy, Faculty of Health Science, Tokoha University bDivision of Cardiology cDepartment of Cardiovascular Surgery, Shizuoka Medical Center, Shizuoka dAnti-aging Center, Ginza Hospital, Tokyo, Japan.
Int J Rehabil Res. 2017 Sep;40(3):193-201. doi: 10.1097/MRR.0000000000000232.
Exercise training has become part of the standard care for patients with cardiovascular disease. We investigated the effects of exercise training on exercise capacity, cardiac function, BMI, and quality of life in patients with atrial fibrillation (AF). We searched for randomized-controlled trials of supervised exercise training versus care without exercise training (the control) in patients with permanent or nonpermanent AF published up to November 2016. Standard mean differences (SMD) or mean differences (MD), and 95% confidence intervals (CIs) were calculated using random-effect models. We identified 259 trials, and after an assessment of relevance, five trials with a combined total of 379 participants were analyzed. In AF patients, exercise training significantly improved exercise capacity and left ventricular ejection fraction compared with the control (SMD: 0.91, 95% CI: 0.70 to 1.12; MD: 4.8%, 95% CIs: 1.56 to 8.03, respectively). Compared with the control, exercise training also significantly reduced BMI (MD: -0.47 kg/m, 95% CIs: -0.89 to -0.06) and significantly improved scores in the 'general health' and 'vitality' sections of the 36-item Short Form Health Status Survey (SMD: 0.71, 95% CIs: 0.30 to 1.12; SMD: 0.81, 95% CIs: 0.40 to 1.23, respectively). Exercise training improved exercise capacity, left ventricular ejection fraction, and some the 36-item Short Form Health Status Survey scores, and reduced BMI in AF patients.
运动训练已成为心血管疾病患者标准治疗的一部分。我们研究了运动训练对心房颤动（AF）患者运动能力、心脏功能、体重指数（BMI）和生活质量的影响。我们检索了截至2016年11月发表的关于永久性或非永久性AF患者接受有监督运动训练与无运动训练（对照）治疗的随机对照试验。使用随机效应模型计算标准平均差（SMD）或平均差（MD）以及95%置信区间（CI）。我们识别出259项试验，经相关性评估后，分析了5项试验，这些试验共有379名参与者。与对照组相比，AF患者进行运动训练显著提高了运动能力和左心室射血分数（SMD分别为：0.91，95%CI：0.70至1.12；MD：4.8%，95%CI：1.56至8.03）。与对照组相比，运动训练还显著降低了BMI（MD：-0.47kg/m²，95%CI：-0.89至-0.06），并显著提高了36项简短健康状况调查问卷“总体健康”和“活力”部分的得分（SMD分别为：0.71，95%CI：0.30至1.12；SMD：0.81，95%CI：0.40至1.23）。运动训练改善了AF患者的运动能力、左心室射血分数以及36项简短健康状况调查问卷的部分得分，并降低了BMI。
