催乳素在变态发育期间对蝌蚪皮肤主动钠转运系统的短期影响。

The short-term effect of prolactin on the active Na transport system of the tadpole skin during metamorphosis.

作者信息

Takada M

出版信息

Comp Biochem Physiol A Comp Physiol. 1986;85(4):755-9. doi: 10.1016/0300-9629(86)90290-2.

Abstract

Prolactin (PRL) induced a transient increase in active Na transport measured as the short circuit current (SCC) of the tadpole skin. Increase in SCC by PRL accelerated as the stage advanced between stages XXII and XXV. Prolactin caused two types of effect on the electric parameters of the active Na transport. In type I, it increased both the electromotive force of the active Na current (ENa) and the resistance to the active Na current (RNa). In type II, it decreased both ENa and RNa. A second application of PRL had no effect on SCC; that is, desensitization to PRL was observed.

摘要

催乳素（PRL）使以蝌蚪皮肤短路电流（SCC）衡量的活性钠转运出现短暂增加。在XXII期至XXV期之间，随着发育阶段的推进，PRL引起的SCC增加加速。催乳素对活性钠转运的电参数产生两种类型的影响。在I型中，它增加了活性钠电流的电动势（ENa）和对活性钠电流的阻力（RNa）。在II型中，它降低了ENa和RNa。第二次应用PRL对SCC没有影响；也就是说，观察到对PRL的脱敏现象。