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贝宁帕拉库过敏性鼻炎的症状:患病率、严重程度及相关因素

Symptoms of allergic rhinitis in Parakou, Benin: Prevalence, severity and associated factors.

作者信息

Flatin M-C, Ade S, Hounkpatin S-H-R, Ametonou B, Vodouhe U-B, Adjibabi W

机构信息

Faculté de médecine, université de Parakou, BP 123, Parakou, Benin.

Faculté de médecine, université de Parakou, BP 123, Parakou, Benin.

出版信息

Eur Ann Otorhinolaryngol Head Neck Dis. 2018 Feb;135(1):33-36. doi: 10.1016/j.anorl.2017.07.003. Epub 2017 Aug 7.

DOI:10.1016/j.anorl.2017.07.003
PMID:28797520
Abstract

AIMS

Allergic rhinitis (AR) is an extremely common disease. This study aimed to determine the prevalence and severity of AR symptoms and potential associated factors, in Parakou, a city in Benin.

MATERIALS AND METHODS

A cross-sectional study was conducted between April and July 2016, involving inhabitants of the city aged between 6 and 65 years. Cluster sampling was carried out. AR symptoms were defined as the simultaneous presence of rhinorrhea, nasal obstruction and sneezing without evidence of respiratory infection. Data were analyzed on EpiData Analysis v2.2.2.183 and then on R.3.2.1.

RESULTS

Three hundred and ninety-five inhabitants were questioned, with a male/female ratio of 1.32, and median age of 19 years. One hundred and forty-one (35.7%) had AR symptoms, 47 (33.3%) had family history of atopy, and 87 (61.7%) had allergic conjunctivitis. The main triggers were house dust (139; 98.5%) and air pollution (111; 78.7%). On multivariate analysis, associated factors were age<18 years (P<0.05), exposure to house dust (P<0.001), and personal history of urticaria (P<0.001) or allergic conjunctivitis (P<0.01). Twenty-eight subjects (19.9%) had persistent symptoms. Forty-three (30.5%) had moderate/severe symptoms, associated with age≥18 years (P<0.01), family history of atopy (P<0.01), personal history of atopic eczema/dermatitis (P<0.01), and presence of a dog or cat at home (P=0.01).

CONCLUSION

The prevalence of AR symptoms in Parakou was high. A non-negligible proportion of symptoms were severe. This disease merits special attention in the city.

摘要

目的

变应性鼻炎(AR)是一种极为常见的疾病。本研究旨在确定贝宁城市帕拉库AR症状的患病率、严重程度及潜在相关因素。

材料与方法

于2016年4月至7月进行了一项横断面研究,纳入了6至65岁的城市居民。采用整群抽样。AR症状定义为同时出现流涕、鼻塞和打喷嚏且无呼吸道感染证据。数据先在EpiData Analysis v2.2.2.183软件上进行分析,然后在R.3.2.1软件上分析。

结果

共询问了395名居民,男女比例为1.32,中位年龄为19岁。141人(35.7%)有AR症状,47人(33.3%)有特应性家族史,87人(61.7%)有过敏性结膜炎。主要诱因是屋尘(139例;98.5%)和空气污染(111例;�8.7%)。多因素分析显示,相关因素为年龄<18岁(P<0.05)、接触屋尘(P<0.001)、有荨麻疹个人史(P<0.001)或过敏性结膜炎个人史(P<%;01)。28名受试者(19.9%)有持续性症状。43人(30.5%)有中度/重度症状,与年龄≥18岁(P<0.01)、特应性家族史(P<0.01)、特应性皮炎/湿疹个人史(P=0.01)及家中养猫或狗(P=0.01)有关。

结论

帕拉库AR症状的患病率较高。有相当比例的症状较为严重。该病在该市值得特别关注。

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