非免疫功能低下患者的骨皮肤棘阿米巴病，预后良好。
Osteo-cutaneous acanthamoebiasis in a non-immunocompromised patient with a favorable outcome.
作者信息
Sharma Megha, Sudhan Shashi Sharma, Sharma Sonali, Megha Kirti, Nada Ritambhra, Khurana Sumeeta
机构信息
Department of Medical Parasitology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Department of Microbiology, Government Medical College Hospital, Jammu, Jammu and Kashmir, India.
出版信息
Parasitol Int. 2017 Dec;66(6):727-730. doi: 10.1016/j.parint.2017.08.003. Epub 2017 Aug 7.
Osteo-cutaneous form is a rare presentation of acanthamoebiasis. We present the first such case from India in an apparently healthy male who developed cutaneous lesion with bone involvement after traumatic inoculation of Acanthamoeba cysts. The diagnosis was established by routine microbiological techniques and confirmed by 18SrRNA gene sequencing. Aggressive therapy with terbinafine, chlorhexidine, rifampicin and co-trimoxazole was successful in clearing the lesion and preventing encephalitis.
骨皮肤型是棘阿米巴病的一种罕见表现形式。我们报告了印度首例此类病例，患者为一名外表健康的男性，在棘阿米巴囊肿经创伤接种后出现了伴有骨受累的皮肤病变。通过常规微生物学技术确诊，并经18SrRNA基因测序证实。使用特比萘芬、氯己定、利福平和复方新诺明进行积极治疗成功清除了病变并预防了脑炎。
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