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经皮关节突关节滑膜囊肿破裂:非手术治疗的前瞻性评估。

Percutaneous Rupture of Zygapophyseal Joint Synovial Cysts: A Prospective Assessment of Nonsurgical Management.

机构信息

Department of Physiatry, Hospital for Special Surgery, New York; and Department of Rehabilitation Medicine, Weill Cornell Medical College, New York, NY.

Department of Physiatry, Hospital for Special Surgery, New York, NY.

出版信息

PM R. 2018 Mar;10(3):245-253. doi: 10.1016/j.pmrj.2017.07.078. Epub 2017 Aug 7.

Abstract

BACKGROUND

Although lumbar zygapophyseal joint synovial cysts are fairly well recognized, they are an uncommon cause of lumbosacral radicular pain. Nonoperative treatments include percutaneous aspiration of the cysts under computed tomography or fluoroscopic guidance with a subsequent corticosteroid injection. However, there are mixed results in terms of long-term outcomes and cyst reoccurrence. This study prospectively evaluates percutaneous ruptures of zygapophyseal joint (Z-joint) synovial cysts for the treatment of lumbosacral radicular pain.

OBJECTIVES

Primary: To determine whether percutaneous rupture of symptomatic Z-joint synovial cysts leads to sustained improvements in radicular pain and function. Secondary: To assess the rates of cyst recurrence and progression to surgical intervention following percutaneous rupture of symptomatic Z-joint synovial cysts.

DESIGN

Prospective cohort study.

SETTING

Outpatient academic spine practice.

PARTICIPANTS

Adults with primary radicular pain due to a facet synovial cyst.

METHODS

Participants underwent fluoroscopically guided percutaneous Z-joint synovial cyst ruptures under standard-of-care practice. Data on pain, physical function, satisfaction, and progression to surgery were collected at 2 weeks, 6 weeks, 3 months, 6 months, and 1 year after rupture. An intention-to-treat analysis was used for assessment of patient-reported outcome measures.

MAIN OUTCOME MEASURES

The Numerical Rating Scale, Oswestry Disability Index, and modified North American Spine Society questionnaires were used to measure pain, function, and satisfaction with the procedure, respectively.

RESULTS

Thirty-five participants were included in the study, and data were analyzed by an independent researcher. Statistically significant changes in Oswestry Disability Index were reported at 2 weeks, 3 months, and 1 year postintervention (P = .034, .040, and .039, respectively). A statistically and clinically significant relief of current pain was reported at 2 weeks (P = .025) and 6 weeks (P = .014) with respect to baseline. Patients showed significant improvements for best pain at 6 weeks with respect to baseline (P = .031). Patients' worst pain showed the greatest amount of improvement with clinically meaningful changes at all time points compared with baseline. Patient-reported satisfaction was found nearly 70% of the time at all time points. Forty percent (14/35) of participants required repeat cyst rupture, and 31% (11/35) required surgical interventions.

CONCLUSIONS

There were statistically and clinically significant improvements in pain and function after percutaneous rupture of Z-joint synovial cysts. In addition, the outcomes support previous retrospective studies indicating that approximately 40% of patients will need surgery. This study provides further research to determine the utility of this procedure and to precisely define a subset of ideal candidates.

LEVEL OF EVIDENCE

Level II.

摘要

背景

尽管腰椎关节突关节滑膜囊肿已得到广泛认识,但它们仍是引起腰骶神经根痛的不常见原因。非手术治疗包括在 CT 或透视引导下经皮抽吸囊肿,并随后进行皮质类固醇注射。然而,在长期疗效和囊肿复发方面,结果存在差异。本研究前瞻性评估经皮破裂关节突关节(Z 关节)滑膜囊肿治疗腰骶神经根痛的效果。

目的

主要目的:确定经皮破裂有症状的 Z 关节滑膜囊肿是否会导致神经根痛和功能持续改善。次要目的:评估经皮破裂有症状的 Z 关节滑膜囊肿后囊肿复发和进展为手术干预的发生率。

设计

前瞻性队列研究。

地点

门诊学术脊柱科。

参与者

因关节突关节滑膜囊肿引起原发性根性疼痛的成年人。

方法

参与者在标准护理实践下接受透视引导下经皮 Z 关节滑膜囊肿破裂。在破裂后 2 周、6 周、3 个月、6 个月和 1 年时收集疼痛、身体功能、满意度和进展至手术的数据。采用意向治疗分析评估患者报告的结果测量值。

主要结局测量指标

数字评分量表、Oswestry 残疾指数和改良北美脊柱协会问卷分别用于测量疼痛、功能和对手术过程的满意度。

结果

35 名参与者纳入研究,由独立研究者进行数据分析。干预后 2 周、3 个月和 1 年时 Oswestry 残疾指数的变化具有统计学意义(P=0.034、0.040 和 0.039)。与基线相比,治疗后 2 周(P=0.025)和 6 周(P=0.014)时当前疼痛的缓解具有统计学和临床意义。与基线相比,6 周时患者最佳疼痛得到显著改善(P=0.031)。与基线相比,患者最差疼痛的改善最大,在所有时间点均具有临床意义的变化。在所有时间点,患者报告的满意度接近 70%。40%(14/35)的患者需要重复囊肿破裂,31%(11/35)需要手术干预。

结论

经皮破裂 Z 关节滑膜囊肿后疼痛和功能均有统计学和临床意义的改善。此外,这些结果支持先前的回顾性研究表明,约 40%的患者需要手术。本研究进一步提供了关于该手术的实用性和准确确定理想候选人群的研究。

证据等级

二级。

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