IgG4相关性垂体炎所致视交叉内脓肿
Intrachiasmatic abscess caused by IgG4-related hypophysitis.
作者信息
Hadjigeorgiou Georgios F, Lund Eva Løbner, Poulsgaard Lars, Feldt-Rasmussen Ulla, Rasmussen Åse Krogh, Wegener Marianne, Fugleholm Kåre
机构信息
Department of Neurosurgery, Academic Hospital Munich-Bogenhausen, Technical University of Munich, Munich, Germany.
Department of Pathology, University Hospital of Copenhagen, Copenhagen, Denmark.
出版信息
Acta Neurochir (Wien). 2017 Nov;159(11):2229-2233. doi: 10.1007/s00701-017-3288-8. Epub 2017 Aug 10.
INTRODUCTION
Autoimmune hypophysitis is a rare disease of the pituitary, which may affect vision by inflammation and compression of the optic chiasm. However, intrachiasmatic abscess formation has not been previously reported.
METHODS
In this study, we report a case of a 29-year-old female with bitemporal hemianopia due to a cystic intrasellar tumor. The patient underwent surgical decompression of the lesion, which was found to be an intrachiasmatic abscess.
RESULTS
The histologic findings were consistent with IgG4 hypophysitis.
CONCLUSION
This rare clinical presentation suggests that in case of a disproportionate degree of visual impairment in relation to the size of the lesion, suspicion should lead to an intrachiasmatic lesion.
引言
自身免疫性垂体炎是一种罕见的垂体疾病，可通过对视交叉的炎症和压迫影响视力。然而，此前尚未有视交叉内脓肿形成的报道。
方法
在本研究中，我们报告了一例29岁女性因鞍内囊性肿瘤导致双颞侧偏盲的病例。患者接受了病变的手术减压，发现是视交叉内脓肿。
结果
组织学检查结果与IgG4垂体炎一致。
结论
这种罕见的临床表现表明，在视力损害程度与病变大小不成比例的情况下，应怀疑存在视交叉内病变。
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