UNICAMP-IMECC-DMA, Rua Sérgio Buarque de Holanda, 651, Campinas, SP, CEP: 13083-859, Brazil.
Bull Math Biol. 2017 Oct;79(10):2273-2301. doi: 10.1007/s11538-017-0330-1. Epub 2017 Aug 10.
The big challenge for the food industry is the attending to demands for minimally processed foods, avoiding intense heat treatments and reducing the addition of chemical preservatives, but at the same time ensuring microbiological safety of these products. Lactic acid bacteria are traditionally used in the production of fermented foods. They are responsible for the production of antimicrobial compounds, such as organic acids and bacteriocins, which are protein compounds with bactericidal effect against related species and bacteria such as Listeria monocytogenes and Staphylococcus aureus. Aiming to study quantitatively the biological control as a technique of conservation, we developed a mathematical model to describe the interaction between lactic acid bacteria and Listeria in the food. The steady state and dynamical trajectories analyses of the model permit us to study the suitability of including lactic acid bacteria in order to reduce the growth of Listeria in food.
食品行业面临的一大挑战是满足对低加工食品的需求,避免剧烈的热处理并减少化学防腐剂的添加,但同时要确保这些产品的微生物安全性。乳酸菌传统上用于发酵食品的生产。它们负责生产抗菌化合物,如有机酸和细菌素,这些都是具有杀菌作用的蛋白质化合物,可对抗相关物种和细菌,如单核细胞增生李斯特菌和金黄色葡萄球菌。为了定量研究生物防治作为一种保存技术,我们开发了一个数学模型来描述食品中乳酸菌和李斯特菌之间的相互作用。模型的稳态和动态轨迹分析使我们能够研究将乳酸菌纳入以减少食品中李斯特菌生长的适宜性。