Mokta Jatinter, Yadav Rahul, Mokta Kiran, Panda Prashant, Ranjan Asha
Professor, Department of Medicine.
Senior Resident, Department of Cardiology.
J Assoc Physicians India. 2017 Aug;65(8):47-50.
Most common cause of jaundice in south east Asia is of infective etiology. Combination of fever with jaundice can cause diagnostic problem as this duo is present in many infective diseases. Timely diagnosis by simple laboratory investigations can save a lot of time and prevent morbidity and mortality. Our main aim was to determine the most common etiology of infectious jaundice in a tertiary care hospital of Himalayan state and to study their clinical profile.
This was a prospective observational study done in one year. All the patients more than 18 years of age presenting with jaundice with bilirubin >1.5mg/dl were taken. The clinical profile was observed and investigations for etiology were done.
Total number of patients studied were 170. Maximum number of patients were 50 (39.4%) in age group less than 30 years and females outnumbered males with 1.8:1 ratio (64.7% v/s 35.3%). Fever was the most common presenting complaint in 127 (74.7%) patients and most common etiology was scrub typhus with 103 patients (60.6%) followed by hepatitis E in 36 patients (21.2%) and leptospirosis in 9 patients (5.3%).
Scrub typhus is the commonest cause of febrile jaundice in Himachal Pradesh. The general physicians should be sensitized for the early diagnosis to reduce mortality.
东南亚黄疸最常见的病因是感染性病因。发热与黄疸同时出现会导致诊断困难,因为这两者在许多感染性疾病中都存在。通过简单的实验室检查及时诊断可以节省大量时间,并预防发病和死亡。我们的主要目的是确定喜马拉雅邦一家三级医院感染性黄疸最常见的病因,并研究其临床特征。
这是一项为期一年的前瞻性观察研究。纳入所有年龄超过18岁、胆红素>1.5mg/dl且出现黄疸的患者。观察其临床特征并进行病因调查。
共研究了170例患者。年龄小于30岁的患者最多,有50例(39.4%),女性多于男性,比例为1.8:1(64.7%对35.3%)。127例(74.7%)患者最常见的主诉是发热,最常见的病因是恙虫病,有103例(60.6%),其次是戊型肝炎36例(21.2%),钩端螺旋体病9例(5.3%)。
恙虫病是喜马偕尔邦发热性黄疸最常见的病因。应提高全科医生对早期诊断的认识以降低死亡率。