恙虫病的临床特征与并发症：喜马拉雅地区医院-based研究 （你提供的“Hospital-Based Study”中的“Based”前少了关键信息，我按照字面准确翻译了，你可以检查下原文是否有误）
Clinical Profile and Complications of Scrub Typhus: Hospital-Based Study in Sub-Himalayan Region.
作者信息
Kumar Ritesh, Thakur Surinder, Bhawani Rajesh, Kanga Anil, Ranjan Asha
机构信息
Senior Resident, Department of Cardiology.
Professor.
出版信息
J Assoc Physicians India. 2016 Dec;64(12):30-34.
BACKGROUND
Scrub typhus is a documented disease in Himachal Pradesh, but there have been no clinico-epidemiological studies in this area. The present study is done with IgM ELISA as a diagnostic test which has higher sensitivity and specificity as most of previous studies had used Weil Felix test as a diagnostic test.
METHODOLOGY
This was a prospective observational study. All the patients more than 18 years of age with positive IgM ELISA for scrub typhus with or without eschar were included. The clinical profile was observed. IgM scrub typhus was done by kit method manufactured by InBios International, Inc.
RESULTS
Total 330 patients were observed. Maximum patients were observed in August, September, and October. Fever was the most common presenting complaint. Eschar was present in 40.61% patients. Complications were seen in 71.2 %.
CONCLUSIONS
The general physicians should be sensitized for the early diagnosis to reduce mortality.
背景
恙虫病在喜马偕尔邦是一种有记录的疾病，但该地区尚未进行临床流行病学研究。本研究采用IgM ELISA作为诊断试验，由于之前大多数研究使用外斐试验作为诊断试验，所以IgM ELISA具有更高的敏感性和特异性。
方法
这是一项前瞻性观察性研究。纳入所有18岁以上IgM ELISA检测恙虫病呈阳性且有或无焦痂的患者。观察其临床特征。IgM恙虫病检测采用InBios International, Inc.生产的试剂盒方法。
结果
共观察了330例患者。8月、9月和10月观察到的患者最多。发热是最常见的主诉。40.61%的患者有焦痂。71.2%的患者出现并发症。
结论
应提高普通医生对早期诊断的认识，以降低死亡率。
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