Centre for Health Economics,University of York,York YO105DD,UK.
Psychol Med. 2018 Apr;48(5):822-833. doi: 10.1017/S0033291717002197. Epub 2017 Aug 14.
Duration of untreated psychosis (DUP) is an important measure of access to care as it predicts prognosis and treatment outcomes. Little is known about potential socioeconomic inequalities in DUP. The aim of this study was to investigate inequalities in DUP associated with socioeconomic deprivation in a national cohort in England.
We analysed a cohort of 887 patients with a first-episode in psychosis using the administrative Mental Health Services Dataset in England for 2012/13-2014/15. We used a Generalised Linear Model to account for non-linearity in DUP and looked at inequalities across the whole distribution of DUP using quantile regression.
The median DUP was 22 days (mean = 74 days) with considerable variations between and within the 31 hospital providers. We found evidence of significant inequalities regarding the level of socioeconomic deprivation. Patients living in the second, third and fourth deprived neighbourhood quintiles faced a 36, 24 and 31 day longer DUP than patients from the least deprived neighbourhoods. Inequalities were more prevalent in higher quantiles of the DUP distribution. Unemployment prolonged DUP by 40 days. Having been in contact with mental health care services prior to the psychosis start significantly reduced the DUP by up to 53 days.
Socioeconomic deprivation is an important factor in explaining inequalities in DUP. Policies to improve equitable access to care should particularly focus on preventing very long delays in treatment and target unemployed patients as well as people that have not been in contact with any mental health professional in the past.
未治疗的精神病期 (DUP) 是衡量获得治疗机会的一个重要指标,因为它可以预测预后和治疗结果。关于 DUP 与社会经济剥夺之间可能存在的不平等现象,人们知之甚少。本研究旨在调查英格兰全国队列中与社会经济贫困相关的 DUP 不平等现象。
我们使用 2012/13 年至 2014/15 年期间英格兰精神卫生服务数据集,对 887 名首次出现精神病的患者进行了队列分析。我们使用广义线性模型来解释 DUP 的非线性,并使用分位数回归来研究 DUP 整个分布中的不平等现象。
DUP 的中位数为 22 天(平均值为 74 天),31 家医院提供者之间和内部存在很大差异。我们发现,社会经济贫困程度存在显著的不平等现象。生活在第二、第三和第四贫困社区五分位数的患者比生活在最贫困社区的患者面临 36、24 和 31 天更长的 DUP。在 DUP 分布的较高分位数中,不平等现象更为普遍。失业使 DUP 延长了 40 天。在精神病发作前与精神卫生保健服务有过接触,可使 DUP 显著减少多达 53 天。
社会经济贫困是解释 DUP 不平等现象的一个重要因素。改善公平获得治疗的政策应特别关注预防治疗的非常长延迟,并针对失业患者以及过去未与任何精神卫生专业人员接触过的人。