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[国际抗癫痫联盟制定的癫痫和发作类型新分类(2017年)]

[New classifications of epilepsies and seizure types created by the International League against Epilepsy (2017)].

作者信息

Belousova E D, Zavadenko N N, Kholin A A, Sharkov A A

机构信息

Neurology, Neurosurgery and Medical Genetics Department of Pediatric Faculty, Pirogov Russian National Research Medical University of the Russia Ministry of Health, Moscow, Russia; Department of Psychoneurology and Epileptology, Research and Clincal Institute of Pediatrics, Pirogov Russian National Research Medical University of the Russia Ministry of Health, Moscow, Russia.

Neurology, Neurosurgery and Medical Genetics Department of Pediatric Faculty, Pirogov Russian National Research Medical University of the Russia Ministry of Health, Moscow, Russia.

出版信息

Zh Nevrol Psikhiatr Im S S Korsakova. 2017;117(7):99-106. doi: 10.17116/jnevro20171177199-106.

Abstract

This review presents the recently published revised classifications of epilepsies and seizure types developed by the International League Against Epilepsy (ILAE). The Classification of Epilepsies includes several diagnostic levels (steps): 1) from seizure type to epilepsy type (generalized/focal/combined generalized and focal/unknown), 2) diagnosis of epilepsy syndrome 3) etiology (genetic/ structural/ infectious/ metabolic/ immune/unknown). A clinician can use any level of the classification. Operational classification of seizure types is replaced by the previous classification that was grounded on the anatomical basis. Seizures are classified by the onset (focal, generalized or unknown). All types of seizures can be motor or non-motor. Focal seizure may evolve to bilateral tonic-clonic (previously called secondary-generalized). Atonic, clonic, tonic, myoclonic seizures and epileptic spasms can be either of focal or generalized onset. Unclassified type of seizure was introduced. New types of seizures (absence with eyelid myoclonia, myoclonic absence, myoclonic atonic and clonic-tonic-clonic seizures) were added. New terminology, definitions and some concepts developed by ILAE are presented.

摘要

本综述介绍了国际抗癫痫联盟(ILAE)最近发布的癫痫和癫痫发作类型的修订分类。癫痫分类包括几个诊断层次(步骤):1)从癫痫发作类型到癫痫类型(全身性/局灶性/全身性和局灶性合并/不明),2)癫痫综合征的诊断,3)病因(遗传/结构/感染/代谢/免疫/不明)。临床医生可以使用分类的任何层次。癫痫发作类型的操作性分类已被以前基于解剖学基础的分类所取代。癫痫发作按发作起始(局灶性、全身性或不明)进行分类。所有类型的癫痫发作都可以是运动性或非运动性的。局灶性发作可能演变为双侧强直阵挛性发作(以前称为继发性全身性发作)。失张力性、阵挛性、强直性、肌阵挛性发作和癫痫性痉挛可以是局灶性或全身性发作起始。引入了未分类的癫痫发作类型。增加了新的癫痫发作类型(伴有眼睑肌阵挛的失神发作、肌阵挛性失神发作、肌阵挛性失张力发作和阵挛 - 强直 - 阵挛性发作)。介绍了ILAE提出的新术语、定义和一些概念。

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