Vadalà G, Buffone A, Giarlotta R, Scuderi G, Calcamo A, Fassari S
Chir Ital. 1986 Oct;38(5):549-54.
Somatostatin, a pituitary hormone with an inhibitory action on gastric secretion, has improved the therapeutic approach to the treatment of the hemorrhagic complications accompanying gastroduodenal ulcer. The authors report on their experience "in doppio cieco" with 84 patients, 53 of whom treated with somatostatin and 31 with cimetidine, the respective success rates being 96.6% and 90.32% in the two treatment groups. It was also noted that the somatostatin-treated group showed earlier arrest of hemorrhage and a lower blood transfusion requirement.
生长抑素是一种对胃分泌有抑制作用的垂体激素,它改善了伴随胃十二指肠溃疡出血并发症的治疗方法。作者报告了他们对84例患者进行“双盲”试验的经验,其中53例用生长抑素治疗,31例用西咪替丁治疗,两个治疗组的成功率分别为96.6%和90.32%。还注意到,生长抑素治疗组出血停止更早,输血需求更低。