Department of Medical Psychology and Medical Sociology, University of Leipzig, Leipzig, Germany.
Department of Gynecology and Obstetrics, University of Leipzig, Leipzig, Germany.
J Pain Symptom Manage. 2017 Dec;54(6):922-928. doi: 10.1016/j.jpainsymman.2017.08.007. Epub 2017 Aug 12.
Cancer patients frequently suffer from fatigue. Recently, the European Organization for Research and Treatment of Cancer (EORTC) Quality of Life group developed a new 12-item fatigue assessment instrument.
The aim of this study was to psychometrically test this questionnaire in comparison with the three-item fatigue scale of the EORTC QLQ-C30.
A sample of 354 patients who were being treated for breast cancer or gynecologic cancer were examined using the new fatigue questionnaire EORTC QLQ-FA12 and the EORTC QLQ-C30 during their hospital stay (t1) and three months after hospital discharge (t2). Confirmatory factorial analyses, item analyses, test-retest reliability analyses, and correlation analyses were performed.
The analyses roughly supported the three-factorial structure of the FA12, which comprised the subscales physical, emotional, and cognitive fatigue. The fit indices of the confirmatory factorial analysis were worse than those of the original article but nevertheless acceptable. Cronbach alpha of the total scale was 0.92; the coefficients of the subscales were between 0.79 and 0.93. The correlation between the EORTC QLQ-FA12 total scale and the fatigue scale of the EORTC QLQ-C30 was 0.69 and the correlation between the t1 and t2 scores was 0.45 for the EORTC QLQ-FA12 total scale and between 0.37 and 0.47 for the subscales.
The psychometric coefficients justify the calculation of a sum score, which can be used by clinicians to assess the general degree of fatigue. Although the three-item fatigue scale of the EORTC QLQ-C30 stresses the physical aspect of fatigue, the new EORTC QLQ-FA12 covers its emotional and cognitive aspects as well.
癌症患者常患有疲劳。最近，欧洲癌症研究与治疗组织（EORTC）生活质量组开发了一种新的 12 项疲劳评估工具。
本研究旨在与 EORTC QLQ-C30 的三个疲劳量表相比，对该问卷进行心理测试。
在住院期间（t1）和出院后三个月（t2），对 354 名正在接受乳腺癌或妇科癌症治疗的患者使用新的 EORTC QLQ-FA12 和 EORTC QLQ-C30 疲劳问卷进行检查。进行了验证性因素分析、项目分析、重测信度分析和相关性分析。
分析大致支持 FA12 的三因素结构，它包含身体、情绪和认知疲劳三个分量表。验证性因素分析的拟合指数虽不如原始文章，但仍可接受。总量表的克朗巴赫 α 为 0.92；分量表的系数在 0.79 至 0.93 之间。EORTC QLQ-FA12 总量表与 EORTC QLQ-C30 疲劳量表之间的相关性为 0.69，EORTC QLQ-FA12 总量表的 t1 和 t2 评分之间的相关性为 0.45，而分量表之间的相关性为 0.37 至 0.47。
心理测量学系数证明了总分的计算是合理的，临床医生可以使用总分来评估疲劳的总体程度。尽管 EORTC QLQ-C30 的三个疲劳量表强调了疲劳的身体方面，但新的 EORTC QLQ-FA12 也涵盖了其情绪和认知方面。
