Smith Zachary L, Eggener Scott E, Murphy Adam B
Department of Surgery, Section of Urology, The University of Chicago Medicine, 5841 S. Maryland Avenue, MC 6038, Chicago, IL, 60637, USA.
Department of Urology, Northwestern University Feinberg School of Medicine, Tarry Building Room 16-703, 300 E. Superior Street, Chicago, IL, 60611, USA.
Curr Urol Rep. 2017 Aug 14;18(10):81. doi: 10.1007/s11934-017-0724-5.
The purpose of this review is to examine prostate cancer racial disparities specific to the African-American population.
African-American men are more likely to be diagnosed with prostate cancer, present at an earlier age; are more likely to have locally advanced or metastatic disease at diagnosis; and have suboptimal outcomes to standard treatments. Prostate cancer treatment requires a nuanced approach, particularly when applying screening, counseling, and management of African-American men. Oncological as well as functional outcomes may differ and are potentially due to a combination of genetic, molecular, behavioral, and socioeconomic factors.
本综述旨在研究非裔美国人群特有的前列腺癌种族差异。
非裔美国男性更易被诊断出患有前列腺癌,且确诊年龄更早;在诊断时更易出现局部晚期或转移性疾病;对标准治疗的效果欠佳。前列腺癌治疗需要一种细致入微的方法,尤其是在对非裔美国男性进行筛查、咨询和管理时。肿瘤学及功能方面的结果可能有所不同,这可能是遗传、分子、行为和社会经济因素共同作用的结果。