Häußler Thomas Christian, von Pückler Kerstin Heike, Thiel Cetina, Enderlein Sylke, Failing Klaus, Ondreka Nele, Kramer Martin, Schmidt Martin Jürgen
1 Department of Veterinary Clinical Sciences, Clinic for Small Animals, Justus Liebig University, Giessen, Germany.
2 Unit for Biomathematics and Data Processing, Faculty of Veterinary Medicine, Justus Liebig University, Giessen, Germany.
J Feline Med Surg. 2018 Jun;20(6):578-586. doi: 10.1177/1098612X17723774. Epub 2017 Aug 15.
Objectives The purpose of this study was to determine differences in normal feline pituitary dimensions in brachycephalic and mesocephalic cats as a basis for establishing cryohypophysectomy in cats. Methods Measurements were performed on sagittal T2-weighted and transverse post-gadolinium T1-weighted or T1 3D fast field echo-weighted MRI images. A total of 32 brachycephalic and 27 mesocephalic cats were examined. Inter-observer reproducibility was assessed by t-test and Bland-Altman analysis. Results The cats were 0.6-15.9 years of age with a body weight range of 1.84-6.60 kg. For brachycephalic cats, the mean pituitary gland sagittal height was 2.15 ± 0.15 mm, pituitary gland transverse height was 2.42 ± 0.21 mm, pituitary gland transverse width was 4.44 ± 0.27 mm and pituitary gland sagittal length was 3.14 ± 0.30 mm. In mesocephalic cats, the pituitary gland dimensions were 2.94 ± 0.16 mm, 3.09 ± 0.26 mm, 4.73 ± 0.31 mm and 4.88 ± 0.30 mm for pituitary gland sagittal height, transverse height, transverse width and sagittal length, respectively. There was a highly significant correlation between brachycephalic and mesocephalic cats and pituitary gland height and length ( P <0.0001), respectively. Sex also had an effect on pituitary gland measurements. Neutering status had no significant effect on hypophyseal measurements. Age had a significant influence on pituitary gland height, width and length in the brachycephalic population. Inter-observer reproducibility was good to excellent. Conclusions and relevance The different pituitary measurements in brachycephalic and mesocephalic cats has to be considered if surgery comes into question. There are ranges in pituitary gland sizes, even among the mesocephalic cat population. Thus, exact measuring of the pituitary gland is crucial before any surgical intervention.
目的 本研究旨在确定短头型和中头型猫正常垂体尺寸的差异，为在猫中建立冷冻垂体切除术奠定基础。方法 在矢状面T2加权和钆增强后横断面T1加权或T1 3D快速场回波加权MRI图像上进行测量。共检查了32只短头型猫和27只中头型猫。通过t检验和布兰德-奥特曼分析评估观察者间的可重复性。结果 猫的年龄为0.6 - 15.9岁，体重范围为1.84 - 6.60 kg。对于短头型猫，垂体矢状高度平均为2.15±0.15 mm，垂体横径高度为2.42±0.21 mm，垂体横径宽度为4.44±0.27 mm，垂体矢状长度为3.14±0.30 mm。在中头型猫中，垂体矢状高度、横径高度、横径宽度和矢状长度的尺寸分别为2.94±0.16 mm、3.09±0.26 mm、4.73±0.31 mm和4.88±0.30 mm。短头型猫和中头型猫与垂体高度和长度之间分别存在高度显著相关性（P<0.0001）。性别也对垂体测量有影响。绝育状态对垂体测量无显著影响。年龄对短头型猫群体的垂体高度、宽度和长度有显著影响。观察者间的可重复性良好至优秀。结论及相关性 如果考虑手术，必须考虑短头型和中头型猫垂体测量的差异。即使在中头型猫群体中，垂体大小也存在一定范围。因此，在任何手术干预之前，精确测量垂体至关重要。
