通过酚类的氧化偶联实现溶剂控制的联苯酚和醌的选择性合成。
Solvent-controlled selective synthesis of biphenols and quinones via oxidative coupling of phenols.
作者信息
More Nagnath Yadav, Jeganmohan Masilamani
机构信息
Department of Chemistry, Indian Institute of Science Education and Research, Pune 411021, India.
出版信息
Chem Commun (Camb). 2017 Aug 24;53(69):9616-9619. doi: 10.1039/c7cc04829g.
PMID:28809969
Abstract
A regioselective synthesis of unsymmetrical and symmetrical biphenols and binaphthols via oxidative coupling of phenols or naphthols in the presence of KSO in CFCOOH under ambient conditions is described. Interestingly, the 1 : 1 ratio of HO and CHCN solvent mixtures at 80 °C instead of CFCOOH provided substituted unsymmetrical quinones. A gram-scale synthesis of biphenols and binaphthols was demonstrated.
摘要
描述了在环境条件下，在CFCOOH中KSO存在下，通过酚或萘酚的氧化偶联区域选择性合成不对称和对称联苯酚及联萘酚的方法。有趣的是，在80℃下，HO与CHCN溶剂混合物以1:1的比例而非CFCOOH提供了取代的不对称醌。展示了联苯酚和联萘酚的克级合成。
Zotero 插件