Banker Tanuj P, McClellan Andrew J, Wilson Benjamin D, Juan Fabiana M, Kuriyan Ajay E, Relhan Nidhi, Chen Felix V, Weichel Eric D, Albini Thomas A, Berrocal Audina M, Sridhar Jay, Gregori Ninel Z, Townsend Justin H, Flynn Harry W
Ophthalmic Surg Lasers Imaging Retina. 2017 Aug 1;48(8):632-637. doi: 10.3928/23258160-20170802-05.
To report the visual and anatomical outcomes and microbiologic spectrum of culture-positive endophthalmitis in open globe injuries (OGIs) with or without intraocular foreign bodies (IOFBs).
A retrospective, interventional case series of OGIs (n = 718) treated between 2004 and 2015. Patients underwent a management protocol for OGI, including systemic broad-spectrum antibiotics, on presentation.
Culture-positive cases of endophthalmitis after open globe repair occurred in 2.1% of eyes (n = 15 of 718 eyes); two eyes had evidence of endophthalmitis on presentation. The most common organism was Staphylococcus species (five of 17 eyes). An IOFB was present in 6.8% of eyes (n = 49 of 718 eyes). All of these eyes received prophylactic intravitreal antimicrobials. In eyes with IOFB, the rate of culture-positive endophthalmitis after initial globe repair was 8.1% (n = 4 of 49 eyes) versus 1.6% (n = 11 of 669 eyes) in eyes without IOFB (P < .01).
Culture-positive endophthalmitis was identified after OGIs more often in eyes with a concurrent IOFB. [Ophthalmic Surg Lasers Imaging Retina. 2017;48:632-637.].
报告开放性眼球损伤（OGI）伴或不伴眼内异物（IOFB）时培养阳性的眼内炎的视力、解剖学转归及微生物谱。
对2004年至2015年间治疗的718例OGI患者进行回顾性、干预性病例系列研究。患者就诊时接受了包括全身应用广谱抗生素在内的OGI治疗方案。
开放性眼球修复术后培养阳性的眼内炎病例占2.1%（718眼中15眼）；2眼就诊时即有眼内炎证据。最常见的病原体是葡萄球菌属（17眼中5眼）。718眼中49眼（6.8%）存在IOFB。所有这些眼均接受了预防性玻璃体内抗微生物药物治疗。在有IOFB的眼中，初次眼球修复术后培养阳性的眼内炎发生率为8.1%（49眼中4眼），而在无IOFB的眼中为1.6%（669眼中11眼）（P <.01）。
OGI后培养阳性的眼内炎在合并IOFB的眼中更为常见。[《眼科手术、激光与影像学视网膜》。2017；48：632 - 637。]
