通过光学相干断层扫描血管造影术上脉络膜低灌注模式鉴别白点综合征
Distinguishing White Dot Syndromes With Patterns of Choroidal Hypoperfusion on Optical Coherence Tomography Angiography.
作者信息
Wang Jay C, Laíns Inês, Sobrin Lucia, Miller John B
出版信息
Ophthalmic Surg Lasers Imaging Retina. 2017 Aug 1;48(8):638-646. doi: 10.3928/23258160-20170802-06.
BACKGROUND AND OBJECTIVE
To compare patterns of choroidal hypoperfusion in white dot syndromes (WDS) using optical coherence tomography angiography (OCTA).
PATIENTS AND METHODS
Consecutive patients with WDS were imaged with either the Zeiss AngioPlex OCT Angiography (Carl Zeiss AG, Oberkochen, Germany) or the AngioVue OCT Angiography (Optovue, Fremont, CA) from February to November 2016. Four patients with acute posterior multifocal placoid pigment epitheliopathy (APMPPE), birdshot chorioretinopathy (BCR), presumed ocular histoplasmosis syndrome (POHS), and multiple evanescent white dot syndrome (MEWDS) were selected. This study was approved by the institutional review board at Massachusetts Eye and Ear.
RESULTS
Unique patterns of choroidal hypoperfusion were observed. In POHS and MEWDS, areas of choroidal hypoperfusion correlated well with clinically observed pathology, but in APMPPE and BCR, they were more widespread.
CONCLUSION
OCTA can identify different patterns of choroidal hypoperfusion in APMPPE, BCR, POHS, and MEWDS, which appears to be a shared feature of WDS. [Ophthalmic Surg Lasers Imaging Retina. 2017;48:638-646.].
背景与目的
使用光学相干断层扫描血管造影（OCTA）比较白点综合征（WDS）中脉络膜低灌注的模式。
患者与方法
2016年2月至11月，连续入选的WDS患者使用蔡司AngioPlex OCT血管造影仪（德国奥伯科亨卡尔蔡司公司）或AngioVue OCT血管造影仪（加利福尼亚州弗里蒙特Optovue公司）进行成像。选取了4例急性后极部多灶性鳞状色素上皮病变（APMPPE）、鸟枪弹样脉络膜视网膜病变（BCR）、疑似眼组织胞浆菌病综合征（POHS）和多发性一过性白点综合征（MEWDS）患者。本研究经马萨诸塞州眼耳医院机构审查委员会批准。
结果
观察到脉络膜低灌注的独特模式。在POHS和MEWDS中，脉络膜低灌注区域与临床观察到的病理改变相关性良好，但在APMPPE和BCR中，低灌注区域更为广泛。
结论
OCTA能够识别APMPPE、BCR、POHS和MEWDS中脉络膜低灌注的不同模式，这似乎是WDS的一个共同特征。[《眼科手术、激光与视网膜成像》。2017；48：638 - 646。]
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